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Gm10499 predicted gene 10499 [ Mus musculus (house mouse) ]

Gene ID: 69717, updated on 27-Nov-2024

Summary

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Official Symbol
Gm10499provided by MGI
Official Full Name
predicted gene 10499provided by MGI
Primary source
MGI:MGI:3702919
See related
Ensembl:ENSMUSG00000121510
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
H-2T7; H2-T7; MumuTL
Expression
Biased expression in duodenum adult (RPKM 75.2), small intestine adult (RPKM 55.2) and 9 other tissues See more
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Genomic context

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See Gm10499 in Genome Data Viewer
Location:
17 B1; 17 18.95 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (36452640..36457092, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (36141748..36146200, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene histocompatibility-2, T region locus 25 Neighboring gene histocompatibility 2, T region pseudogene Neighboring gene RIKEN cDNA 2410017I17 gene Neighboring gene histocompatibility 2, T region locus 26 Neighboring gene akirin 1 pseudogene Neighboring gene akirin 1 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Major histocompatibility complex (Mhc) class Ib gene duplications, organization and expression patterns in mouse strain C57BL/6. Ohtsuka M, et al. BMC Genomics, 2008 Apr 17. PMID 18416856, Free PMC Article
  2. Organization and evolution of the class I gene family in the major histocompatibility complex of the C57BL/10 mouse. Weiss EH, et al. Nature, 1984 Aug 23-29. PMID 6088985
  3. A physical map of the Q region of B1O.P. Litaker W, et al. Mamm Genome, 1996 Mar. PMID 8833240
  4. Clusters of genes encoding mouse transplantation antigens. Steinmetz M, et al. Cell, 1982 Mar. PMID 6280871
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

General protein information

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Preferred Names
gene 10499
Names
MHC class I antigen
histocompatibility 2, T region locus 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001370818.1 → NP_001357747.1  gene 10499 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AI605939, CD541295, CT030728
    Related
    ENSMUST00000292570.1
    Conserved Domains (2) summary
    cd07698
    Location:204 → 296
    IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
    pfam00129
    Location:23 → 200
    MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2

  2. NM_001370819.1 → NP_001357748.1  gene 10499 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AI605939, CD541295, CT030728
    Conserved Domains (2) summary
    cd07698
    Location:204 → 296
    IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
    pfam00129
    Location:23 → 200
    MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2

  3. NM_001370820.1 → NP_001357749.1  gene 10499 isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AI605939, CD541295, CT030728
    Conserved Domains (3) summary
    cd07698
    Location:204 → 295
    IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
    pfam00129
    Location:23 → 200
    MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2
    pfam06623
    Location:296 → 320
    MHC_I_C; MHC_I C-terminus

  4. NM_001370821.1 → NP_001357750.1  gene 10499 isoform 4 precursor

    Status: VALIDATED

    Source sequence(s)
    AI605939, CD541295, CT030728
    Conserved Domains (2) summary
    cd07698
    Location:204 → 295
    IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
    pfam00129
    Location:23 → 200
    MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    36452640..36457092 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017317765.2 → XP_017173254.1  gene 10499 isoform X1

    Related
    ENSMUST00000292569.1
    Conserved Domains (3) summary
    cd07698
    Location:212 → 304
    IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
    pfam00129
    Location:31 → 208
    MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2
    pfam06623
    Location:346 → 370
    MHC_I_C; MHC_I C-terminus
Nucleotide Protein Strain
Heading Accession and Version

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