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silS copper/silver sensor histidine kinase SilS [ Klebsiella quasivariicola ]

Gene ID: 69758411, updated on 12-Dec-2024

Summary

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Gene symbol
silS
Gene description
copper/silver sensor histidine kinase SilS
Locus tag
LGM30_RS28400
Gene type
protein coding
Organism
Klebsiella quasivariicola (strain: 08A119, nat-host: Homo sapiens)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella
Old locus tag
LGM30_28430
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Genomic context

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Location:
plasmid: pKqv_08A119_1

NZ_CP084769.1Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene silver-binding protein SilE Neighboring gene copper/silver response regulator transcription factor SilR Neighboring gene Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC Neighboring gene cation efflux system protein CusF

Genomic regions, transcripts, and products

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Genomic Sequence:
NZ_CP084769.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transmissible silver resistance readily evolves in high-risk clone isolates of Klebsiella pneumoniae. Hanczvikkel A, et al. Acta Microbiol Immunol Hung, 2018 Aug 1. PMID 30043621
  2. Evolution of a Heavy Metal Homeostasis/Resistance Island Reflects Increasing Copper Stress in Enterobacteria. Staehlin BM, et al. Genome Biol Evol, 2016 Feb 17. PMID 26893455, Free PMC Article
  3. Silver resistance in Gram-negative bacteria: a dissection of endogenous and exogenous mechanisms. Randall CP, et al. J Antimicrob Chemother, 2015 Apr. PMID 25567964, Free PMC Article
  4. Molecular basis for resistance to silver cations in Salmonella. Gupta A, et al. Nat Med, 1999 Feb. PMID 9930866

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
copper/silver sensor histidine kinase SilS

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NZ_CP084769.1 Reference assembly

    Range
    366869..368344 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_003032875.1 MULTISPECIES: copper/silver sensor histidine kinase SilS [Enterobacterales]

    See identical proteins and their annotated locations for WP_003032875.1

    UniProtKB/TrEMBL
    A0A0E1CMJ4, A0A237R484, A0A246ARI3, A0A2N4Z2V2, A0A2P9E0I9, A0A2S1FUV8, A0A2S1PK83, A0A443W7T6, A0A7W3B9Z1, A0AAD2U511, A0AAE3UPX1, A0AAE4MWK1, A0AAX0ACY2, G7RV21, R4WK38
    Conserved Domains (1) summary
    PRK09835
    Location:1 → 483
    PRK09835; Cu(+)/Ag(+) sensor histidine kinase
Nucleotide Protein
Heading Accession and Version