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Polr3gl polymerase (RNA) III (DNA directed) polypeptide G like [ Mus musculus (house mouse) ]

Gene ID: 69870, updated on 27-Nov-2024

Summary

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Official Symbol
Polr3glprovided by MGI
Official Full Name
polymerase (RNA) III (DNA directed) polypeptide G likeprovided by MGI
Primary source
MGI:MGI:1917120
See related
Ensembl:ENSMUSG00000028104 AllianceGenome:MGI:1917120
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2010003I19Rik
Summary
Enables chromatin binding activity. Predicted to be involved in transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. Is expressed in alimentary system; eye; nervous system; retina; and stomach. Orthologous to human POLR3GL (RNA polymerase III subunit GL). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in limb E14.5 (RPKM 9.3), bladder adult (RPKM 8.8) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Polr3gl in Genome Data Viewer
Location:
3 F2.1; 3 41.93 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (96485188..96501497, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (96577872..96594181, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene hemojuvelin BMP co-receptor Neighboring gene STARR-positive B cell enhancer mm9_chr3:96351291-96351592 Neighboring gene STARR-positive B cell enhancer ABC_E6082 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:96361830-96361983 Neighboring gene STARR-seq mESC enhancer starr_08439 Neighboring gene predicted gene 15441 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:96368663-96368826 Neighboring gene thioredoxin interacting protein Neighboring gene STARR-seq mESC enhancer starr_08441 Neighboring gene STARR-positive B cell enhancer ABC_E6083 Neighboring gene STARR-seq mESC enhancer starr_08442 Neighboring gene STARR-positive B cell enhancer ABC_E3451 Neighboring gene ankyrin repeat domain 34A Neighboring gene RIKEN cDNA 6330549D23 gene Neighboring gene predicted gene, 52628 Neighboring gene Lix1-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Functions of paralogous RNA polymerase III subunits POLR3G and POLR3GL in mouse development. Wang X, et al. Proc Natl Acad Sci U S A, 2020 Jul 7. PMID 32576691, Free PMC Article
  2. Gene duplication and neofunctionalization: POLR3G and POLR3GL. Renaud M, et al. Genome Res, 2014 Jan. PMID 24107381, Free PMC Article
  3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  4. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (3)  1 citation

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables chromatin binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in transcription by RNA polymerase III ISO
Inferred from Sequence Orthology
more info
  
involved_in transcription by RNA polymerase III ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
part_of RNA polymerase III complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of RNA polymerase III complex ISO
Inferred from Sequence Orthology
more info
 PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 PubMed 

General protein information

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Preferred Names
DNA-directed RNA polymerase III subunit RPC7-like
Names
DNA-directed RNA polymerase III subunit G-like
RNA polymerase III subunit C7-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001293701.1 → NP_001280630.1  DNA-directed RNA polymerase III subunit RPC7-like isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation from a downstream start codon compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AC122037
    Consensus CDS
    CCDS79982.1
    UniProtKB/TrEMBL
    D3YXS1
    Related
    ENSMUSP00000118943.2, ENSMUST00000145001.2

  2. NM_027241.4 → NP_081517.2  DNA-directed RNA polymerase III subunit RPC7-like isoform 1

    See identical proteins and their annotated locations for NP_081517.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC122037, AK008069
    Consensus CDS
    CCDS17641.1
    UniProtKB/Swiss-Prot
    Q8R0C0, Q9D8G0
    Related
    ENSMUSP00000089544.4, ENSMUST00000091924.10
    Conserved Domains (1) summary
    pfam11705
    Location:21 → 201
    RNA_pol_3_Rpc31; DNA-directed RNA polymerase III subunit Rpc31

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    96485188..96501497 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030252811.2 → XP_030108671.1  DNA-directed RNA polymerase III subunit RPC7-like isoform X1

    UniProtKB/Swiss-Prot
    Q8R0C0, Q9D8G0
    Conserved Domains (1) summary
    pfam11705
    Location:21 → 201
    RNA_pol_3_Rpc31; DNA-directed RNA polymerase III subunit Rpc31
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8R0C0.2 GenPept UniProtKB/Swiss-Prot:Q8R0C0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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