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Zfp995 zinc finger protein 995 [ Mus musculus (house mouse) ]

Gene ID: 70081, updated on 27-Nov-2024

Summary

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Official Symbol
Zfp995provided by MGI
Official Full Name
zinc finger protein 995provided by MGI
Primary source
MGI:MGI:1917331
See related
Ensembl:ENSMUSG00000078546 AllianceGenome:MGI:1917331
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2210404O09Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in CNS E18 (RPKM 1.4), bladder adult (RPKM 1.3) and 19 other tissues See more
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Genomic context

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See Zfp995 in Genome Data Viewer
Location:
17 A3.3; 17 11.4 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (22097888..22129060, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (21878907..21910085, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_42017 Neighboring gene zinc finger protein 760 pseudogene Neighboring gene zinc finger protein 820 Neighboring gene predicted gene, 31758 Neighboring gene STARR-seq mESC enhancer starr_42018 Neighboring gene STARR-seq mESC enhancer starr_42019 Neighboring gene STARR-seq mESC enhancer starr_42020 Neighboring gene nuclease-sensitive element-binding protein 1 pseudogene Neighboring gene zinc finger protein 942 Neighboring gene STARR-positive B cell enhancer ABC_E11628

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC70081

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001256493.1 → NP_001243422.1  uncharacterized protein LOC70081

    See identical proteins and their annotated locations for NP_001243422.1

    Status: VALIDATED

    Source sequence(s)
    AI180682, BY741152, CT009755
    Consensus CDS
    CCDS57051.1
    UniProtKB/TrEMBL
    E9Q6M3
    Related
    ENSMUSP00000139581.2, ENSMUST00000190066.7
    Conserved Domains (4) summary
    COG5048
    Location:201 → 436
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:325 → 345
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:162 → 177
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:13 → 52
    KRAB; KRAB box

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    22097888..22129060 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036160782.1 → XP_036016675.1  uncharacterized protein LOC70081 isoform X1

    UniProtKB/TrEMBL
    E9Q6M3
    Conserved Domains (4) summary
    COG5048
    Location:201 → 436
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:325 → 345
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:162 → 177
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:13 → 52
    KRAB; KRAB box

  2. XM_036160780.1 → XP_036016673.1  uncharacterized protein LOC70081 isoform X1

    UniProtKB/TrEMBL
    E9Q6M3
    Conserved Domains (4) summary
    COG5048
    Location:201 → 436
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:325 → 345
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:162 → 177
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:13 → 52
    KRAB; KRAB box

  3. XM_036160781.1 → XP_036016674.1  uncharacterized protein LOC70081 isoform X1

    UniProtKB/TrEMBL
    E9Q6M3
    Conserved Domains (4) summary
    COG5048
    Location:201 → 436
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:325 → 345
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:162 → 177
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:13 → 52
    KRAB; KRAB box

  4. XM_030250038.2 → XP_030105898.1  uncharacterized protein LOC70081 isoform X1

    UniProtKB/TrEMBL
    E9Q6M3
    Conserved Domains (4) summary
    COG5048
    Location:201 → 436
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:325 → 345
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:162 → 177
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:13 → 52
    KRAB; KRAB box

  5. XM_036160779.1 → XP_036016672.1  uncharacterized protein LOC70081 isoform X1

    UniProtKB/TrEMBL
    E9Q6M3
    Conserved Domains (4) summary
    COG5048
    Location:201 → 436
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:325 → 345
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:162 → 177
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:13 → 52
    KRAB; KRAB box

  6. XM_030250042.2 → XP_030105902.1  uncharacterized protein LOC70081 isoform X2

    Conserved Domains (5) summary
    COG5048
    Location:237 → 380
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:269 → 289
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:162 → 177
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box
    pfam13465
    Location:198 → 222
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein Strain
Heading Accession and Version

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