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tspo-1 TspO/MBR family protein [ Caenorhabditis elegans ]

Gene ID: 7040157, updated on 4-Jan-2025

Summary

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Official Symbol
tspo-1
Official Full Name
TspO/MBR family protein
Primary source
WormBase:WBGene00077771
Locus tag
CELE_C41G7.9
See related
AllianceGenome:WB:WBGene00077771
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be located in membrane. Predicted to be active in mitochondrial outer membrane. Orthologous to several human genes including TSPO (translocator protein). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See tspo-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
5
Sequence:
Chromosome: I; NC_003279.8 (9514998..9516776, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene Kinesin motor domain-containing protein Neighboring gene Messenger RNA-binding inhibitor of apoptosis 1 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. BPA interferes with StAR-mediated mitochondrial cholesterol transport to induce germline dysfunctions. Chen Y, et al. Reprod Toxicol, 2019 Dec. PMID 31445225, Free PMC Article
  2. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
  3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrial outer membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
TspO/MBR family protein
NP_001251116.1
  • Confirmed by transcript evidence
NP_001251117.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    9514998..9516776 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001264188.4 → NP_001251117.1  TspO/MBR family protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001251117.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B3WFW9
    Conserved Domains (1) summary
    pfam03073
    Location:38 → 161
    TspO_MBR; TspO/MBR family

  2. NM_001264187.4 → NP_001251116.1  TspO/MBR family protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001251116.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    C7FZU5
    Conserved Domains (1) summary
    pfam03073
    Location:79 → 202
    TspO_MBR; TspO/MBR family
Nucleotide Protein
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