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Tmem30c transmembrane protein 30C [ Mus musculus (house mouse) ]

Gene ID: 71027, updated on 4-Jan-2025

Summary

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Official Symbol
Tmem30cprovided by MGI
Official Full Name
transmembrane protein 30Cprovided by MGI
Primary source
MGI:MGI:1918277
See related
Ensembl:ENSMUSG00000022753 AllianceGenome:MGI:1918277
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cdc50c; 4933401B01Rik; 4933409A18Rik
Summary
Predicted to be involved in phospholipid translocation. Predicted to be located in membrane. Predicted to be active in Golgi apparatus; endoplasmic reticulum; and plasma membrane. Orthologous to human TMEM30CP (transmembrane protein 30C, pseudogene). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Restricted expression toward testis adult (RPKM 17.8) See more
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Genomic context

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See Tmem30c in Genome Data Viewer
Location:
16 C1.1; 16 34.22 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (57086502..57122185, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (57266139..57301904, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_41078 Neighboring gene STARR-positive B cell enhancer ABC_E8637 Neighboring gene predicted gene, 16892 Neighboring gene TBC1 domain family, member 23 Neighboring gene nitrilase family, member 2 Neighboring gene STARR-positive B cell enhancer ABC_E11617 Neighboring gene STARR-positive B cell enhancer mm9_chr16:57231379-57231680 Neighboring gene STARR-seq mESC enhancer starr_41080 Neighboring gene STARR-seq mESC enhancer starr_41081 Neighboring gene STARR-seq mESC enhancer starr_41082 Neighboring gene STARR-seq mESC enhancer starr_41083 Neighboring gene predicted gene, 26800 Neighboring gene RIKEN cDNA 4921517D16 gene Neighboring gene cms small ribosomal subunit 1 Neighboring gene filamin A interacting protein 1-like Neighboring gene STARR-seq mESC enhancer starr_41085 Neighboring gene STARR-positive B cell enhancer ABC_E11618 Neighboring gene chaperonin containing Tcp1, subunit 8 (theta) pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Characterization and expression of mouse Cdc50c during spermatogenesis. Xu P, et al. Acta Biochim Biophys Sin (Shanghai), 2007 Oct. PMID 17928922
  2. Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice. Horiuchi K, et al. Cell Rep, 2018 Apr 3. PMID 29617656
  3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in phospholipid translocation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cell cycle control protein 50C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027651.1 → NP_081927.1  cell cycle control protein 50C

    See identical proteins and their annotated locations for NP_081927.1

    Status: VALIDATED

    Source sequence(s)
    AK016597, AK161475, CT025521
    Consensus CDS
    CCDS49876.1
    UniProtKB/Swiss-Prot
    A9C447, Q9D4D7
    UniProtKB/TrEMBL
    A9C448
    Related
    ENSMUSP00000112989.2, ENSMUST00000119407.8
    Conserved Domains (1) summary
    pfam03381
    Location:53 → 333
    CDC50; LEM3 (ligand-effect modulator 3) family / CDC50 family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    57086502..57122185 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030249283.2 → XP_030105143.1  cell cycle control protein 50C isoform X3

    Conserved Domains (1) summary
    pfam03381
    Location:14 → 285
    CDC50; LEM3 (ligand-effect modulator 3) family / CDC50 family

  2. XM_011246014.4 → XP_011244316.1  cell cycle control protein 50C isoform X1

    See identical proteins and their annotated locations for XP_011244316.1

    UniProtKB/Swiss-Prot
    A9C447, Q9D4D7
    UniProtKB/TrEMBL
    A9C448
    Conserved Domains (1) summary
    pfam03381
    Location:53 → 333
    CDC50; LEM3 (ligand-effect modulator 3) family / CDC50 family

  3. XM_017317134.2 → XP_017172623.1  cell cycle control protein 50C isoform X2

    UniProtKB/TrEMBL
    A9C448
    Conserved Domains (1) summary
    pfam03381
    Location:53 → 327
    CDC50; LEM3 (ligand-effect modulator 3) family / CDC50 family

  4. XM_011246012.4 → XP_011244314.1  cell cycle control protein 50C isoform X1

    See identical proteins and their annotated locations for XP_011244314.1

    UniProtKB/Swiss-Prot
    A9C447, Q9D4D7
    UniProtKB/TrEMBL
    A9C448
    Conserved Domains (1) summary
    pfam03381
    Location:53 → 333
    CDC50; LEM3 (ligand-effect modulator 3) family / CDC50 family

  5. XM_030249284.2 → XP_030105144.1  cell cycle control protein 50C isoform X4

    Conserved Domains (1) summary
    pfam03381
    Location:1 → 234
    CDC50; LEM3 (ligand-effect modulator 3) family / CDC50 family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D4D7.2 GenPept UniProtKB/Swiss-Prot:Q9D4D7

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