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Mfap3l microfibrillar-associated protein 3-like [ Mus musculus (house mouse) ]

Gene ID: 71306, updated on 27-Nov-2024

Summary

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Official Symbol
Mfap3lprovided by MGI
Official Full Name
microfibrillar-associated protein 3-likeprovided by MGI
Primary source
MGI:MGI:1918556
See related
Ensembl:ENSMUSG00000031647 AllianceGenome:MGI:1918556
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
NYD-sp9; mKIAA0626; 4933428A15Rik; 5430405D20Rik
Summary
Predicted to be located in several cellular components, including cell junction; nucleoplasm; and plasma membrane. Is expressed in central nervous system. Orthologous to human MFAP3L (microfibril associated protein 3 like). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in testis adult (RPKM 23.6), frontal lobe adult (RPKM 7.6) and 7 other tissues See more
Orthologs
human all
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Genomic context

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See Mfap3l in Genome Data Viewer
Location:
8 B3.1; 8 30.86 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (61085859..61129765)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (60632825..60676731)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53433 Neighboring gene STARR-seq mESC enhancer starr_21561 Neighboring gene predicted gene, 34730 Neighboring gene STARR-seq mESC enhancer starr_21563 Neighboring gene predicted gene, 53434 Neighboring gene predicted gene 45650

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Feb 28. PMID 12693553
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cell junction IEA
Inferred from Electronic Annotation
more info
  
located_in cell junction ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
microfibrillar-associated protein 3-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177881.1 → NP_001171352.1  microfibrillar-associated protein 3-like isoform a precursor

    See identical proteins and their annotated locations for NP_001171352.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an alternate 5' UTR exon compared to variant 1. Variants 1, 2, and 3 all encode the same isoform (a).
    Source sequence(s)
    AC121923, AK133407
    Consensus CDS
    CCDS22321.1
    UniProtKB/Swiss-Prot
    Q80TV6, Q8BJA9, Q9D3X9
    Related
    ENSMUSP00000124330.2, ENSMUST00000161702.8
    Conserved Domains (2) summary
    cd00096
    Location:64 → 139
    Ig; Immunoglobulin domain
    smart00410
    Location:55 → 142
    IG_like; Immunoglobulin like

  2. NM_001177882.1 → NP_001171353.1  microfibrillar-associated protein 3-like isoform a precursor

    See identical proteins and their annotated locations for NP_001171353.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has an alternate 5' UTR exon compared to variant 1. Variants 1, 2, and 3 all encode the same isoform (a).
    Source sequence(s)
    AC121923, AK016959
    Consensus CDS
    CCDS22321.1
    UniProtKB/Swiss-Prot
    Q80TV6, Q8BJA9, Q9D3X9
    Related
    ENSMUSP00000034066.4, ENSMUST00000034066.4
    Conserved Domains (2) summary
    cd00096
    Location:64 → 139
    Ig; Immunoglobulin domain
    smart00410
    Location:55 → 142
    IG_like; Immunoglobulin like

  3. NM_001293769.1 → NP_001280698.1  microfibrillar-associated protein 3-like isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an alternate exon compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a.
    Source sequence(s)
    AC121923
    Consensus CDS
    CCDS80877.1
    UniProtKB/Swiss-Prot
    Q9D3X9
    Related
    ENSMUSP00000124136.2, ENSMUST00000161421.2
    Conserved Domains (2) summary
    smart00410
    Location:7 → 39
    IG_like; Immunoglobulin like
    cl11960
    Location:7 → 39
    Ig; Immunoglobulin domain

  4. NM_027756.5 → NP_082032.1  microfibrillar-associated protein 3-like isoform a precursor

    See identical proteins and their annotated locations for NP_082032.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) and variants 2 and 3 encode the same isoform (a).
    Source sequence(s)
    AC121923, CJ132157
    Consensus CDS
    CCDS22321.1
    UniProtKB/Swiss-Prot
    Q80TV6, Q8BJA9, Q9D3X9
    Related
    ENSMUSP00000125139.2, ENSMUST00000160719.8
    Conserved Domains (2) summary
    cd00096
    Location:64 → 139
    Ig; Immunoglobulin domain
    smart00410
    Location:55 → 142
    IG_like; Immunoglobulin like

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    61085859..61129765
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D3X9.1 GenPept UniProtKB/Swiss-Prot:Q9D3X9

Gene LinkOut

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