Ints8 integrator complex subunit 8 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ints8provided by MGI
Official Full Name: integrator complex subunit 8provided by MGI
Primary source: MGI:MGI:1919906
See related: Ensembl:ENSMUSG00000040738 AllianceGenome:MGI:1919906
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 2810013E07Rik; D130008D20Rik
Summary: Predicted to be involved in snRNA 3'-end processing. Predicted to be part of integrator complex. Is expressed in cerebral cortex intermediate zone; cerebral cortex subventricular zone; cerebral cortex ventricular layer; and cortical plate. Orthologous to human INTS8 (integrator complex subunit 8). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Broad expression in CNS E11.5 (RPKM 10.6), liver E14 (RPKM 8.4) and 25 other tissues See more
Orthologs: human all
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Genomic context

Location:: 4 A1; 4 5.08 cM

Exon count:: 29

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	4	NC_000070.7 (11199158..11254264, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	4	NC_000070.6 (11199158..11254265, complement)

Chromosome 4 - NC_000070.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (5)
Gene trapped (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

UniSTS:496751 (e-PCR)
- UniSTS:496751

Ccne2 (e-PCR), detects polymorphism
- UniSTS:496751

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in snRNA 3'-end processing	IBA Inferred from Biological aspect of Ancestor more info
involved_in snRNA 3'-end processing	IEA Inferred from Electronic Annotation more info
involved_in snRNA processing	ISO Inferred from Sequence Orthology more info
involved_in snRNA processing	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of integrator complex	IBA Inferred from Biological aspect of Ancestor more info
part_of integrator complex	ISO Inferred from Sequence Orthology more info
part_of integrator complex	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: integrator complex subunit 8

Names: int8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.