U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Xlr4c X-linked lymphocyte-regulated 4C [ Mus musculus (house mouse) ]

Gene ID: 72891, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
Xlr4cprovided by MGI
Official Full Name
X-linked lymphocyte-regulated 4Cprovided by MGI
Primary source
MGI:MGI:3574099
See related
Ensembl:ENSMUSG00000031362 AllianceGenome:MGI:3574099
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2900036K24Rik
Summary
Predicted to be involved in meiotic cell cycle and spermatid development. Predicted to be active in synaptonemal complex. Is expressed in several structures, including brain; hemolymphoid system; hindgut diverticulum; placenta; and yolk sac. [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in placenta adult (RPKM 19.1) and thymus adult (RPKM 3.6) See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Xlr4c in Genome Data Viewer
Location:
X A7.3; X 37.29 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (72277682..72286736, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (73234076..73243130, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene X-linked lymphocyte-regulated 4B Neighboring gene factor 8-associated gene A Neighboring gene X-linked lymphocyte-regulated 3C Neighboring gene STARR-seq mESC enhancer starr_47345 Neighboring gene X-linked lymphocyte-regulated 5C

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. At Term, XmO and XpO Mouse Placentas Show Differences in Glucose Metabolism in the Trophectoderm-Derived Outer Zone. He N, et al. Front Cell Dev Biol, 2017. PMID 28680878, Free PMC Article
  2. Xlr3b is a new imprinted candidate for X-linked parent-of-origin effects on cognitive function in mice. Davies W, et al. Nat Genet, 2005 Jun. PMID 15908950
  3. Identification of a cluster of X-linked imprinted genes in mice. Raefski AS, et al. Nat Genet, 2005 Jun. PMID 15908953
  4. Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. Tamplin OJ, et al. Dev Biol, 2011 Dec 15. PMID 22008794
  5. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in meiotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in spermatid development IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in synaptonemal complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
X-linked lymphocyte-regulated 4C

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_183094.3 → NP_898917.2  X-linked lymphocyte-regulated 4C

    See identical proteins and their annotated locations for NP_898917.2

    Status: VALIDATED

    Source sequence(s)
    AA190046, AK166871
    Consensus CDS
    CCDS41012.1
    UniProtKB/TrEMBL
    Q3TKR2, Q9JJQ8
    Related
    ENSMUSP00000110176.2, ENSMUST00000114530.8
    Conserved Domains (1) summary
    pfam04803
    Location:60 → 188
    Cor1; Cor1/Xlr/Xmr conserved region

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    72277682..72286736 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030251507.2 → XP_030107367.1  X-linked lymphocyte-regulated 4C isoform X1

    UniProtKB/TrEMBL
    Q3TKR2, Q9JJQ8
    Related
    ENSMUSP00000070117.3, ENSMUST00000068551.9
    Conserved Domains (1) summary
    pfam04803
    Location:60 → 188
    Cor1; Cor1/Xlr/Xmr conserved region

  2. XM_030251506.1 → XP_030107366.1  X-linked lymphocyte-regulated 4C isoform X1

    UniProtKB/TrEMBL
    Q3TKR2, Q9JJQ8
    Conserved Domains (1) summary
    pfam04803
    Location:60 → 188
    Cor1; Cor1/Xlr/Xmr conserved region
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools