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METD_RS02585 ActS/PrrB/RegB family redox-sensitive histidine kinase [ Methylorubrum extorquens DM4 ]

Gene ID: 72987890, updated on 29-Sep-2023

Summary

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Gene symbol
METD_RS02585
Gene description
ActS/PrrB/RegB family redox-sensitive histidine kinase
Locus tag
METD_RS02585
Gene type
protein coding
Organism
Methylorubrum extorquens DM4 (strain: DM4, type-material: type strain of Methylobacterium dichloromethanicum)
Lineage
Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales; Methylobacteriaceae; Methylorubrum
Old locus tag
METD_I0573; METDI0573
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Genomic context

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Sequence:
NC_012988.1 (542450..543844)

NC_012988.1Genomic Context describing neighboring genes Neighboring gene SprT family zinc-dependent metalloprotease Neighboring gene polyhydroxyalkanoate depolymerase Neighboring gene ActR/PrrA/RegA family redox response regulator transcription factor Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_012988.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. RegA, the regulator of the two-component system RegB/RegA of Brucella suis, is a controller of both oxidative respiration and denitrification required for chronic infection in mice. Abdou E, et al. Infect Immun, 2013 Jun. PMID 23529617, Free PMC Article
  2. RegB/RegA, a highly conserved redox-responding global two-component regulatory system. Elsen S, et al. Microbiol Mol Biol Rev, 2004 Jun. PMID 15187184, Free PMC Article
  3. Topological analysis of the membrane-localized redox-responsive sensor kinase PrrB from Rhodobacter sphaeroides 2.4.1. Ouchane S, et al. J Biol Chem, 1999 Jun 11. PMID 10358089
  4. A global signal transduction system regulates aerobic and anaerobic CO2 fixation in Rhodobacter sphaeroides. Qian Y, et al. J Bacteriol, 1996 Jan. PMID 8550404, Free PMC Article

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
ActS/PrrB/RegB family redox-sensitive histidine kinase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_012988.1 Reference assembly

    Range
    542450..543844
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_015821039.1 ActS/PrrB/RegB family redox-sensitive histidine kinase [Methylorubrum extorquens]

    See identical proteins and their annotated locations for WP_015821039.1

    UniProtKB/TrEMBL
    A0A1S1P4J3, C7CAK0
    Conserved Domains (3) summary
    cd00082
    Location:207 → 268
    HisKA; Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via ...
    smart00387
    Location:328 → 433
    HATPase_c; Histidine kinase-like ATPases
    COG0642
    Location:139 → 441
    BaeS; Signal transduction histidine kinase [Signal transduction mechanisms]
Nucleotide Protein
Heading Accession and Version