serpinb1.L serpin family B member 1 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: serpinb1.L
Official Full Name: serpin family B member 1 L homeolog
Primary source: Xenbase:XB-GENE-1217270
Locus tag: XELAEV_180315591mg
See related: EnsemblRapid:ENSXLAG00005009685 AllianceGenome:Xenbase:XB-GENE-1217270
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: lei; pi2; mnei; m/nei; elanh2; serpinb1
Summary: Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in cytoplasm and extracellular space. Orthologous to human SERPINB1 (serpin family B member 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

Location:: chromosome: 6L

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	6L	NC_054381.1 (90600896..90629528)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	6L	NC_030734.1 (83962370..83984149)

Chromosome 6L - NC_054381.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables serine-type endopeptidase inhibitor activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in extracellular space	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: leukocyte elastase inhibitor

Names: serpin B1; serpin peptidase inhibitor, clade B (ovalbumin), member 1 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001095913.1 → NP_001089382.1 leukocyte elastase inhibitor

See identical proteins and their annotated locations for NP_001089382.1

Status: PROVISIONAL

Source sequence(s)

BC094073

UniProtKB/Swiss-Prot

Q52L45

UniProtKB/TrEMBL

A0A974CMT7

Related

ENSXLAP00005028339.1, ENSXLAT00005029076.1

Conserved Domains (1) summary

cl00137
Location:4 → 377

SERPIN; SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate ...