U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Aldh3b3 aldehyde dehydrogenase 3 family, member B3 [ Mus musculus (house mouse) ]

Gene ID: 73458, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
Aldh3b3provided by MGI
Official Full Name
aldehyde dehydrogenase 3 family, member B3provided by MGI
Primary source
MGI:MGI:1920708
See related
Ensembl:ENSMUSG00000037263 AllianceGenome:MGI:1920708
Gene type
protein coding
RefSeq status
INFERRED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700055N04Rik
Summary
Enables aldehyde dehydrogenase (NAD+) activity. Predicted to be involved in aldehyde metabolic process. Located in cytoplasm and plasma membrane. Is expressed in olfactory epithelium; retina inner nuclear layer; retina layer; and retina outer nuclear layer. Orthologous to human ALDH3B2 (aldehyde dehydrogenase 3 family member B2). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Broad expression in bladder adult (RPKM 7.2), testis adult (RPKM 5.6) and 18 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Aldh3b3 in Genome Data Viewer
Location:
19 A; 19 3.68 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (4008733..4022419)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (3958732..3972419)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene aldehyde dehydrogenase 3 family, member B1 Neighboring gene predicted gene, 42059 Neighboring gene STARR-positive B cell enhancer ABC_E7624 Neighboring gene unc-93 homolog B1, TLR signaling regulator Neighboring gene STARR-seq mESC enhancer starr_45335 Neighboring gene aldehyde dehydrogenase 3 family, member B2 Neighboring gene STARR-positive B cell enhancer ABC_E7625 Neighboring gene predicted gene, 52386 Neighboring gene aminoacylase 3

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Mouse aldehyde dehydrogenase ALDH3B2 is localized to lipid droplets via two C-terminal tryptophan residues and lipid modification. Kitamura T, et al. Biochem J, 2015 Jan 1. PMID 25286108
  2. Distinct roles of androgen receptor, estrogen receptor alpha, and BCL6 in the establishment of sex-biased DNA methylation in mouse liver. AlOgayil N, et al. Sci Rep, 2021 Jul 2. PMID 34215813, Free PMC Article
  3. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables 3-chloroallyl aldehyde dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables aldehyde dehydrogenase (NAD+) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables aldehyde dehydrogenase (NAD+) activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables aldehyde dehydrogenase [NAD(P)+] activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in aldehyde metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within aldehyde metabolic process IC
Inferred by Curator
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
aldehyde dehydrogenase family 3 member B3
NP_082821.2
XP_006531905.1
XP_006531906.1
XP_006531907.1
XP_006531908.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028545.2 → NP_082821.2  aldehyde dehydrogenase family 3 member B3

    Status: INFERRED

    Source sequence(s)
    AC133523
    Consensus CDS
    CCDS57128.1
    UniProtKB/Swiss-Prot
    J3QMK6, Q9D9K6
    Related
    ENSMUSP00000136334.2, ENSMUST00000179433.8
    Conserved Domains (1) summary
    cd07132
    Location:18 → 460
    ALDH_F3AB; Aldehyde dehydrogenase family 3 members A1, A2, and B1 and related proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    4008733..4022419
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006531843.3 → XP_006531906.1  aldehyde dehydrogenase family 3 member B3 isoform X2

    Conserved Domains (1) summary
    cl11961
    Location:18 → 329
    ALDH-SF; NAD(P)+-dependent aldehyde dehydrogenase superfamily

  2. XM_006531844.5 → XP_006531907.1  aldehyde dehydrogenase family 3 member B3 isoform X3

    Conserved Domains (1) summary
    cl11961
    Location:18 → 329
    ALDH-SF; NAD(P)+-dependent aldehyde dehydrogenase superfamily

  3. XM_006531845.5 → XP_006531908.1  aldehyde dehydrogenase family 3 member B3 isoform X4

    Conserved Domains (1) summary
    cl11961
    Location:18 → 329
    ALDH-SF; NAD(P)+-dependent aldehyde dehydrogenase superfamily

  4. XM_006531842.3 → XP_006531905.1  aldehyde dehydrogenase family 3 member B3 isoform X1

    Conserved Domains (1) summary
    cl11961
    Location:18 → 418
    ALDH-SF; NAD(P)+-dependent aldehyde dehydrogenase superfamily
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
J3QMK6.1 GenPept UniProtKB/Swiss-Prot:J3QMK6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools