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sirt3.2.L sirtuin (silent mating type information regulation 2 homolog) 3, gene 2 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 734623, updated on 4-Jan-2025

Summary

Official Symbol
sirt3.2.L
Official Full Name
sirtuin (silent mating type information regulation 2 homolog) 3, gene 2 L homeolog
Primary source
Xenbase:XB-GENE-6255591
Locus tag
XELAEV_18016856mg
See related
EnsemblRapid:ENSXLAG00005023268 AllianceGenome:Xenbase:XB-GENE-6255591
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
sirt3.2; sirt3.2.S
Summary
Predicted to enable NAD+ binding activity; metal ion binding activity; and transferase activity. Orthologous to human SIRT3 (sirtuin 3). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See sirt3.2.L in Genome Data Viewer
Location:
chromosome: 3L
Exon count:
10
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (21088583..21105953)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (10326342..10343672, complement)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene carbohydrate sulfotransferase 1 like L homeolog Neighboring gene lamina-associated polypeptide 2 Neighboring gene transmembrane protein 263 L homeolog Neighboring gene RIC8 guanine nucleotide exchange factor B L homeolog Neighboring gene regulatory factor X4 L homeolog

Genomic regions, transcripts, and products

General protein information

Preferred Names
sirtuin (silent mating type information regulation 2 homolog) 3, gene 2 L homeolog
Names
sirtuin (silent mating type information regulation 2 homolog) 3, gene 2 S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001096098.1NP_001089567.1  sirtuin (silent mating type information regulation 2 homolog) 3, gene 2 L homeolog

    See identical proteins and their annotated locations for NP_001089567.1

    Status: PROVISIONAL

    Source sequence(s)
    BC097921
    UniProtKB/TrEMBL
    Q4V7G8
    Related
    ENSXLAP00005068673.1, ENSXLAT00005070207.1
    Conserved Domains (1) summary
    cd01408
    Location:90322
    SIRT1; SIRT1: Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    21088583..21105953
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041585260.1XP_041441194.1  sirtuin (silent mating type information regulation 2 homolog) 3, gene 2 L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1MHJ4
    Conserved Domains (1) summary
    cl00195
    Location:84296
    SIR2; SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+, ...
  2. XM_041585259.1XP_041441193.1  sirtuin (silent mating type information regulation 2 homolog) 3, gene 2 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A1L8GWP9, A0A974HSF1
    Conserved Domains (1) summary
    cd01408
    Location:125357
    SIRT1; Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins ...