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Hyls1 Hyls1 centriolar and ciliogenesis associated [ Drosophila melanogaster (fruit fly) ]

Gene ID: 7354432, updated on 9-Dec-2024

Summary

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Official Symbol
Hyls1provided by FlyBase
Official Full Name
Hyls1 centriolar and ciliogenesis associatedprovided by FlyBase
Primary source
FLYBASE:FBgn0087041
Locus tag
Dmel_CG42231
See related
AllianceGenome:FB:FBgn0087041
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG42231; Dmel\CG42231; hyls1; HYLS1
Summary
Predicted to be involved in cilium assembly. Located in centriole and ciliary basal body. Human ortholog(s) of this gene implicated in hydrolethalus syndrome 1. Orthologous to human HYLS1 (HYLS1 centriolar and ciliogenesis associated). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Hyls1 in Genome Data Viewer
Location:
35F1-35F12; 2-52 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (16342430..16352628, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (16342430..16352628, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene chiffon Neighboring gene uncharacterized protein Neighboring gene calcium-binding protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Analysis of Hydrolethalus Syndrome Protein HYLS1 in Ciliogenesis and Spermatogenesis in Drosophila. Hou Y, et al. Front Cell Dev Biol, 2020. PMID 32509774, Free PMC Article
  2. A screen for genes expressed in the olfactory organs of Drosophila melanogaster identifies genes involved in olfactory behaviour. Tunstall NE, et al. PLoS One, 2012. PMID 22530061, Free PMC Article
  3. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
  4. Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species. Sanfilippo P, et al. Genome Biol, 2017 Nov 30. PMID 29191225, Free PMC Article
  5. Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster. Liu X, et al. RNA, 2017 Dec. PMID 28851752, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

  • transcript and protein products are distinct from overlapping gene

Gene Ontology Provided by FlyBase

Component Evidence Code Pubs
located_in centriole IDA
Inferred from Direct Assay
more info
 PubMed 
located_in ciliary basal body IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Hyls1 centriolar and ciliogenesis associated
Names
CG42231-PA
Hyls1-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    16342430..16352628 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001144356.3 → NP_001137828.1  Hyls1 centriolar and ciliogenesis associated [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001137828.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7YZW2
    Conserved Domains (1) summary
    pfam15311
    Location:197 → 234
    HYLS1_C; Hydrolethalus syndrome protein 1 C-terminus
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B7YZW2 B7YZW2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials