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hemA 5-aminolevulinate synthase [ Anaplasma marginale str. Florida ]

Gene ID: 7398498, updated on 9-Jan-2025

Summary

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Gene symbol
hemA
Gene description
5-aminolevulinate synthase
Locus tag
AMF_RS09515
Gene type
protein coding
Organism
Anaplasma marginale str. Florida (strain: Florida, nat-host: cattle)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria; Rickettsiales; Anaplasmataceae; Anaplasma
Old locus tag
AMF_905
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Genomic context

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Sequence:
NC_012026.1 (1075194..1076402, complement)

NC_012026.1Genomic Context describing neighboring genes Neighboring gene penicillin-binding protein 2 Neighboring gene protein translocase subunit SecF Neighboring gene YraN family protein Neighboring gene tyrosine--tRNA ligase Neighboring gene tRNA-Lys

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_012026.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structure of the Mitochondrial Aminolevulinic Acid Synthase, a Key Heme Biosynthetic Enzyme. Brown BL, et al. Structure, 2018 Apr 3. PMID 29551290, Free PMC Article
  2. Crystal structure of 5-aminolevulinate synthase, the first enzyme of heme biosynthesis, and its link to XLSA in humans. Astner I, et al. EMBO J, 2005 Sep 21. PMID 16121195, Free PMC Article
  3. Expression of the Rhodobacter sphaeroides hemA and hemT genes, encoding two 5-aminolevulinic acid synthase isozymes. Neidle EL, et al. J Bacteriol, 1993 Apr. PMID 8468290, Free PMC Article
  4. Identification of a novel Anaplasma marginale appendage-associated protein that localizes with actin filaments during intraerythrocytic infection. Stich RW, et al. Infect Immun, 2004 Dec. PMID 15557651, Free PMC Article
  5. Sequence and expression analysis of a surface antigen gene family of the rickettsia Anaplasma marginale. Viseshakul N, et al. Gene, 2000 Jul 25. PMID 10925201

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
5-aminolevulinate synthase
WP_010268779.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_012026.1 Reference assembly

    Range
    1075194..1076402 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_010268779.1 5-aminolevulinate synthase [Anaplasma marginale]

    UniProtKB/TrEMBL
    B9KH26
    Conserved Domains (1) summary
    PRK09064
    Location:2 → 402
    PRK09064; 5-aminolevulinate synthase; Validated