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WNT5A Wnt family member 5A [ Homo sapiens (human) ]

Gene ID: 7474, updated on 27-Nov-2024

Summary

Official Symbol
WNT5Aprovided by HGNC
Official Full Name
Wnt family member 5Aprovided by HGNC
Primary source
HGNC:HGNC:12784
See related
Ensembl:ENSG00000114251 MIM:164975; AllianceGenome:HGNC:12784
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
hWNT5A
Summary
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Expression
Broad expression in urinary bladder (RPKM 9.1), endometrium (RPKM 7.3) and 19 other tissues See more
Orthologs
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Genomic context

See WNT5A in Genome Data Viewer
Location:
3p14.3
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (55465715..55505263, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (55499921..55539460, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (55499743..55521334, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124906243 Neighboring gene long intergenic non-protein coding RNA 2030 Neighboring gene uncharacterized LOC124909383 Neighboring gene ReSE screen-validated silencer GRCh37_chr3:55508124-55508358 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:55515943-55516553 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:55522958-55523468 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:55523469-55523980 Neighboring gene VISTA enhancer hs1472 Neighboring gene NANOG hESC enhancer GRCh37_chr3:55545884-55546385 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:55553529-55554030 Neighboring gene WNT5A antisense RNA 1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:55589475-55589976 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:55605047-55605674 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:55605675-55606302 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:55610793-55611315 Neighboring gene ReSE screen-validated silencer GRCh37_chr3:55612193-55612392 Neighboring gene ReSE screen-validated silencer GRCh37_chr3:55615025-55615237 Neighboring gene uncharacterized LOC105377100 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19976 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr3:55649046-55649821 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr3:55649822-55650596 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:55681397-55681910 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:55681911-55682424 Neighboring gene ELKS/RAB6-interacting/CAST family member 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19977 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19978 Neighboring gene ERC2 intronic transcript 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Envelope surface glycoprotein gp120 env HIV-1 gp120 upregulates the expression of WNT5a in human neural stem cells PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables chemoattractant activity involved in axon guidance IEA
Inferred from Electronic Annotation
more info
 
enables cytokine activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables frizzled binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables frizzled binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables frizzled binding TAS
Traceable Author Statement
more info
PubMed 
enables phospholipid binding TAS
Traceable Author Statement
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein domain specific binding IEA
Inferred from Electronic Annotation
more info
 
enables receptor ligand activity IC
Inferred by Curator
more info
PubMed 
enables receptor tyrosine kinase-like orphan receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in JNK cascade IEA
Inferred from Electronic Annotation
more info
 
involved_in Wnt signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in Wnt signaling pathway, calcium modulating pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in Wnt signaling pathway, calcium modulating pathway NAS
Non-traceable Author Statement
more info
PubMed 
involved_in Wnt signaling pathway, planar cell polarity pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in Wnt signaling pathway, planar cell polarity pathway TAS
Traceable Author Statement
more info
PubMed 
acts_upstream_of activation of protein kinase B activity IDA
Inferred from Direct Assay
more info
PubMed 
involved_in anterior/posterior axis specification, embryo IEA
Inferred from Electronic Annotation
more info
 
involved_in atrial septum development IEA
Inferred from Electronic Annotation
more info
 
involved_in axon extension involved in axon guidance IEA
Inferred from Electronic Annotation
more info
 
involved_in axon guidance ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in canonical Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cartilage development IEA
Inferred from Electronic Annotation
more info
 
involved_in cell fate commitment IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cellular response to calcium ion IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cellular response to lipopolysaccharide IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cellular response to retinoic acid ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cellular response to transforming growth factor beta stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cellular response to type II interferon IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cervix development IEA
Inferred from Electronic Annotation
more info
 
involved_in chemoattraction of serotonergic neuron axon ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in chemorepulsion of dopaminergic neuron axon ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cochlea morphogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in convergent extension involved in axis elongation IEA
Inferred from Electronic Annotation
more info
 
involved_in convergent extension involved in organogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in embryonic digit morphogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in embryonic skeletal system development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in epithelial cell migration IEA
Inferred from Electronic Annotation
more info
 
involved_in epithelial cell proliferation involved in mammary gland duct elongation IEA
Inferred from Electronic Annotation
more info
 
involved_in epithelial to mesenchymal transition IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in establishment of epithelial cell apical/basal polarity IEA
Inferred from Electronic Annotation
more info
 
involved_in establishment of planar polarity IEA
Inferred from Electronic Annotation
more info
 
involved_in excitatory synapse assembly TAS
Traceable Author Statement
more info
PubMed 
involved_in face development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in fibroblast growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in genitalia development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in heart looping IEA
Inferred from Electronic Annotation
more info
 
involved_in hematopoietic stem cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in hindgut morphogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in hypophysis morphogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in inflammatory response IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in inhibitory synapse assembly TAS
Traceable Author Statement
more info
PubMed 
involved_in keratinocyte differentiation IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in kidney development IEA
Inferred from Electronic Annotation
more info
 
involved_in lateral sprouting involved in mammary gland duct morphogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in lens development in camera-type eye ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in lung development IEA
Inferred from Electronic Annotation
more info
 
involved_in macrophage derived foam cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in male gonad development IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in mammary gland branching involved in thelarche IEA
Inferred from Electronic Annotation
more info
 
involved_in meiotic nuclear division IEA
Inferred from Electronic Annotation
more info
 
involved_in melanocyte proliferation IEA
Inferred from Electronic Annotation
more info
 
involved_in mesenchymal cell proliferation IEA
Inferred from Electronic Annotation
more info
 
involved_in mesenchymal-epithelial cell signaling IEA
Inferred from Electronic Annotation
more info
 
involved_in mesodermal to mesenchymal transition involved in gastrulation IEA
Inferred from Electronic Annotation
more info
 
involved_in midbrain dopaminergic neuron differentiation TAS
Traceable Author Statement
more info
PubMed 
involved_in midgut development IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of axon extension involved in axon guidance IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within negative regulation of canonical Wnt signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in negative regulation of cell proliferation in midbrain NAS
Non-traceable Author Statement
more info
PubMed 
involved_in negative regulation of epithelial cell proliferation IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of fat cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of fibroblast growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of melanin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of mesenchymal cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of prostatic bud formation IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of synapse assembly IEA
Inferred from Electronic Annotation
more info
 
involved_in neural tube closure IEA
Inferred from Electronic Annotation
more info
 
involved_in neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in neuron differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in non-canonical Wnt signaling pathway TAS
Traceable Author Statement
more info
PubMed 
involved_in notochord morphogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in olfactory bulb interneuron development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in optic cup formation involved in camera-type eye development ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in paraxial mesoderm formation IEA
Inferred from Electronic Annotation
more info
 
involved_in pericardium morphogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of positive regulation of JUN kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of MAPK cascade IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of T cell chemotaxis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of angiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of apoptotic signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of cartilage development IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of cell-cell adhesion mediated by cadherin IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of chemokine production IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of cytokine production involved in immune response IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of endocytosis IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of endothelial cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of endothelial cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of fibroblast proliferation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of gene expression ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of hematopoietic stem cell proliferation IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of inflammatory response IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of interleukin-1 beta production IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of interleukin-1 beta production ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of interleukin-6 production IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of interleukin-8 production IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of macrophage activation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of macrophage cytokine production IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of meiotic nuclear division IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of mesenchymal cell proliferation IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of neuron projection arborization ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of neuron projection development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of non-canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of ossification IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of protein catabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in positive regulation of protein kinase C activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of protein localization to synapse TAS
Traceable Author Statement
more info
PubMed 
involved_in positive regulation of response to cytokine stimulus IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of thymocyte apoptotic process IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of timing of anagen IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of tumor necrosis factor production ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of type I interferon-mediated signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of type II interferon production IEA
Inferred from Electronic Annotation
more info
 
involved_in post-anal tail morphogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in postsynapse assembly TAS
Traceable Author Statement
more info
PubMed 
involved_in postsynaptic modulation of chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 
involved_in presynapse assembly TAS
Traceable Author Statement
more info
PubMed 
involved_in primary heart field specification IEA
Inferred from Electronic Annotation
more info
 
involved_in primitive streak formation IEA
Inferred from Electronic Annotation
more info
 
involved_in protein localization IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of branching involved in mammary gland duct morphogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of canonical NF-kappaB signal transduction ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of inflammatory response NAS
Non-traceable Author Statement
more info
PubMed 
involved_in regulation of postsynapse organization IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of postsynapse organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of postsynaptic cytosolic calcium ion concentration IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of postsynaptic cytosolic calcium ion concentration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of synapse organization IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of synapse organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in secondary heart field specification IEA
Inferred from Electronic Annotation
more info
 
involved_in secondary palate development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in somitogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in thymocyte apoptotic process IEA
Inferred from Electronic Annotation
more info
 
involved_in type B pancreatic cell development IEA
Inferred from Electronic Annotation
more info
 
involved_in urinary bladder development IEA
Inferred from Electronic Annotation
more info
 
involved_in uterus development IEA
Inferred from Electronic Annotation
more info
 
involved_in vagina development IEA
Inferred from Electronic Annotation
more info
 
involved_in ventricular septum development IEA
Inferred from Electronic Annotation
more info
 
involved_in wound healing IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi lumen TAS
Traceable Author Statement
more info
 
located_in Schaffer collateral - CA1 synapse IEA
Inferred from Electronic Annotation
more info
 
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 
located_in clathrin-coated endocytic vesicle membrane TAS
Traceable Author Statement
more info
 
colocalizes_with collagen-containing extracellular matrix HDA PubMed 
located_in endocytic vesicle membrane TAS
Traceable Author Statement
more info
 
located_in endoplasmic reticulum lumen TAS
Traceable Author Statement
more info
 
located_in extracellular exosome TAS
Traceable Author Statement
more info
 
located_in extracellular region TAS
Traceable Author Statement
more info
PubMed 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in glutamatergic synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
 
located_in postsynapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein Wnt-5a
Names
WNT-5A protein
epididymis secretory sperm binding protein
wingless-type MMTV integration site family, member 5A

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_031992.2 RefSeqGene

    Range
    22957..44548
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001256105.1NP_001243034.1  protein Wnt-5a isoform 2 precursor

    See identical proteins and their annotated locations for NP_001243034.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1.
    Source sequence(s)
    AC121764, AK290869, BU742635, DB224740
    Consensus CDS
    CCDS58835.1
    UniProtKB/TrEMBL
    Q6DK41
    Related
    ENSP00000420104.1, ENST00000497027.5
    Conserved Domains (1) summary
    cd19347
    Location:54365
    Wnt_Wnt5a; Wnt domain found in protein Wnt-5a and similar proteins
  2. NM_001377271.1NP_001364200.1  protein Wnt-5a isoform 2 precursor

    Status: REVIEWED

    Source sequence(s)
    AC121764
    Consensus CDS
    CCDS58835.1
    UniProtKB/TrEMBL
    Q6DK41
    Conserved Domains (1) summary
    cd19347
    Location:54365
    Wnt_Wnt5a; Wnt domain found in protein Wnt-5a and similar proteins
  3. NM_001377272.1NP_001364201.1  protein Wnt-5a isoform 2 precursor

    Status: REVIEWED

    Source sequence(s)
    AC121764
    Consensus CDS
    CCDS58835.1
    UniProtKB/TrEMBL
    Q6DK41
    Conserved Domains (1) summary
    cd19347
    Location:54365
    Wnt_Wnt5a; Wnt domain found in protein Wnt-5a and similar proteins
  4. NM_003392.7NP_003383.4  protein Wnt-5a isoform 1 precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes isoform 1.
    Source sequence(s)
    AC121764, AK090582, BC064694, BU742635
    Consensus CDS
    CCDS46850.1
    UniProtKB/Swiss-Prot
    A8K4A4, P41221, Q6P278
    UniProtKB/TrEMBL
    A0A384N611, Q6DK41
    Related
    ENSP00000264634.4, ENST00000264634.9
    Conserved Domains (1) summary
    cd19347
    Location:69380
    Wnt_Wnt5a; Wnt domain found in protein Wnt-5a and similar proteins

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    55465715..55505263 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047448855.1XP_047304811.1  protein Wnt-5a isoform X1

  2. XM_047448853.1XP_047304809.1  protein Wnt-5a isoform X1

  3. XM_047448857.1XP_047304813.1  protein Wnt-5a isoform X1

  4. XM_047448854.1XP_047304810.1  protein Wnt-5a isoform X1

  5. XM_047448859.1XP_047304815.1  protein Wnt-5a isoform X1

  6. XM_011534086.3XP_011532388.1  protein Wnt-5a isoform X1

    See identical proteins and their annotated locations for XP_011532388.1

    UniProtKB/TrEMBL
    Q6DK41
    Conserved Domains (1) summary
    cd19347
    Location:54365
    Wnt_Wnt5a; Wnt domain found in protein Wnt-5a and similar proteins
  7. XM_017007128.2XP_016862617.1  protein Wnt-5a isoform X1

    UniProtKB/TrEMBL
    Q6DK41
    Conserved Domains (1) summary
    cd19347
    Location:54365
    Wnt_Wnt5a; Wnt domain found in protein Wnt-5a and similar proteins
  8. XM_047448858.1XP_047304814.1  protein Wnt-5a isoform X1

  9. XM_047448862.1XP_047304818.1  protein Wnt-5a isoform X1

  10. XM_047448861.1XP_047304817.1  protein Wnt-5a isoform X1

  11. XM_047448856.1XP_047304812.1  protein Wnt-5a isoform X1

  12. XM_047448860.1XP_047304816.1  protein Wnt-5a isoform X1

  13. XM_047448852.1XP_047304808.1  protein Wnt-5a isoform X1

  14. XM_017007127.2XP_016862616.1  protein Wnt-5a isoform X2

    UniProtKB/TrEMBL
    Q6DK41
  15. XM_011534088.3XP_011532390.1  protein Wnt-5a isoform X1

    See identical proteins and their annotated locations for XP_011532390.1

    UniProtKB/TrEMBL
    Q6DK41
    Conserved Domains (1) summary
    cd19347
    Location:54365
    Wnt_Wnt5a; Wnt domain found in protein Wnt-5a and similar proteins
  16. XM_011534089.2XP_011532391.1  protein Wnt-5a isoform X1

    See identical proteins and their annotated locations for XP_011532391.1

    UniProtKB/TrEMBL
    Q6DK41
    Conserved Domains (1) summary
    cd19347
    Location:54365
    Wnt_Wnt5a; Wnt domain found in protein Wnt-5a and similar proteins

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    55499921..55539460 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054347752.1XP_054203727.1  protein Wnt-5a isoform X1

  2. XM_054347756.1XP_054203731.1  protein Wnt-5a isoform X1

  3. XM_054347755.1XP_054203730.1  protein Wnt-5a isoform X1

  4. XM_054347753.1XP_054203728.1  protein Wnt-5a isoform X1

  5. XM_054347754.1XP_054203729.1  protein Wnt-5a isoform X1

  6. XM_054347750.1XP_054203725.1  protein Wnt-5a isoform X1

  7. XM_054347751.1XP_054203726.1  protein Wnt-5a isoform X2

  8. XM_054347757.1XP_054203732.1  protein Wnt-5a isoform X1

  9. XM_054347758.1XP_054203733.1  protein Wnt-5a isoform X1