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Nxnl2 nucleoredoxin-like 2 [ Mus musculus (house mouse) ]

Gene ID: 75124, updated on 4-Jan-2025

Summary

Official Symbol
Nxnl2provided by MGI
Official Full Name
nucleoredoxin-like 2provided by MGI
Primary source
MGI:MGI:1922374
See related
Ensembl:ENSMUSG00000021396 AllianceGenome:MGI:1922374
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rdcvf2; 4930519N16Rik
Summary
Acts upstream of or within sensory perception of smell and visual perception. Orthologous to human NXNL2 (nucleoredoxin like 2). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Broad expression in ovary adult (RPKM 4.3), testis adult (RPKM 1.9) and 18 other tissues See more
Orthologs
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Genomic context

See Nxnl2 in Genome Data Viewer
Location:
13 A5; 13 26.08 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (51324256..51329227)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (51168706..51175191)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32613 Neighboring gene STARR-seq mESC enhancer starr_34498 Neighboring gene STARR-seq mESC enhancer starr_34499 Neighboring gene STARR-seq mESC enhancer starr_34501 Neighboring gene STARR-seq mESC enhancer starr_34502 Neighboring gene STARR-seq mESC enhancer starr_34504 Neighboring gene RIKEN cDNA 9430083A17 gene Neighboring gene STARR-seq mESC enhancer starr_34507 Neighboring gene STARR-seq mESC enhancer starr_34508 Neighboring gene spindlin 1 Neighboring gene STARR-seq mESC enhancer starr_34509 Neighboring gene H2A histone family, pseudogene 2 Neighboring gene VISTA enhancer mm1300 Neighboring gene predicted gene, 29787 Neighboring gene STARR-seq mESC enhancer starr_34511 Neighboring gene STARR-positive B cell enhancer mm9_chr13:51370075-51370375

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (3)  1 citation

General protein information

Preferred Names
nucleoredoxin-like protein 2
Names
rod-derived cone viability factor 2
NP_001405689.1
NP_083449.1
XP_006517023.1
XP_006517024.1
XP_006517025.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001418760.1NP_001405689.1  nucleoredoxin-like protein 2

    Status: VALIDATED

    Source sequence(s)
    AC160122
    UniProtKB/Swiss-Prot
    Q91WB0, Q9D531
  2. NM_029173.5NP_083449.1  nucleoredoxin-like protein 2

    See identical proteins and their annotated locations for NP_083449.1

    Status: VALIDATED

    Source sequence(s)
    AC160122
    Consensus CDS
    CCDS26511.1
    UniProtKB/Swiss-Prot
    Q91WB0, Q9D531
    Related
    ENSMUSP00000021828.5, ENSMUST00000021828.6
    Conserved Domains (1) summary
    cd02964
    Location:10144
    TryX_like_family; Tryparedoxin (TryX)-like family; composed of TryX and related proteins including nucleoredoxin (NRX), rod-derived cone viability factor (RdCVF) and the nematode homolog described as a 16-kD class of TRX. Most members of this family, except RdCVF, are ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    51324256..51329227
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006516962.5XP_006517025.1  nucleoredoxin-like protein 2 isoform X2

    See identical proteins and their annotated locations for XP_006517025.1

    UniProtKB/Swiss-Prot
    Q91WB0, Q9D531
    Conserved Domains (1) summary
    cd02964
    Location:10144
    TryX_like_family; Tryparedoxin (TryX)-like family; composed of TryX and related proteins including nucleoredoxin (NRX), rod-derived cone viability factor (RdCVF) and the nematode homolog described as a 16-kD class of TRX. Most members of this family, except RdCVF, are ...
  2. XM_006516961.5XP_006517024.1  nucleoredoxin-like protein 2 isoform X2

    See identical proteins and their annotated locations for XP_006517024.1

    UniProtKB/Swiss-Prot
    Q91WB0, Q9D531
    Conserved Domains (1) summary
    cd02964
    Location:10144
    TryX_like_family; Tryparedoxin (TryX)-like family; composed of TryX and related proteins including nucleoredoxin (NRX), rod-derived cone viability factor (RdCVF) and the nematode homolog described as a 16-kD class of TRX. Most members of this family, except RdCVF, are ...
  3. XM_006516960.2XP_006517023.1  nucleoredoxin-like protein 2 isoform X2

    See identical proteins and their annotated locations for XP_006517023.1

    UniProtKB/Swiss-Prot
    Q91WB0, Q9D531
    Conserved Domains (1) summary
    cd02964
    Location:10144
    TryX_like_family; Tryparedoxin (TryX)-like family; composed of TryX and related proteins including nucleoredoxin (NRX), rod-derived cone viability factor (RdCVF) and the nematode homolog described as a 16-kD class of TRX. Most members of this family, except RdCVF, are ...