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CDK5RAP2 CDK5 regulatory subunit associated protein 2 [ Gallus gallus (chicken) ]

Gene ID: 771445, updated on 17-Aug-2024

Summary

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Symbol
CDK5RAP2provided by CGNC
Full Name
CDK5 regulatory subunit associated protein 2provided by CGNC
Primary source
CGNC:5260
See related
Ensembl:ENSGALG00010027929
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
EGFL5
Orthologs
human mouse all
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Genomic context

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See CDK5RAP2 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
40
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 17 NC_052548.1 (5170346..5248860, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 17 NC_052589.1 (4584202..4662679, complement)

Chromosome 17 - NC_052548.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112529989 Neighboring gene uncharacterized LOC124417280 Neighboring gene uncharacterized LOC121107094 Neighboring gene multiple EGF-like-domains 9 Neighboring gene uncharacterized LOC101749517 Neighboring gene collagen type XXVII alpha 1 chain Neighboring gene microRNA 6696

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables gamma-tubulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription cis-regulatory region binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in centriole replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chromosome segregation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of mitotic spindle orientation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in microtubule bundle formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of centriole replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of microtubule polymerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of mitotic cell cycle spindle assembly checkpoint IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in microtubule organizing center IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in microtubule plus-end IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitotic spindle pole IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in pericentriolar material IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
CDK5 regulatory subunit-associated protein 2
Names
EGF-like-domain, multiple 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052548.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    5170346..5248860 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040649272.2 → XP_040505206.1  CDK5 regulatory subunit-associated protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8V1AGH3
    Related
    ENSGALP00010041440.1, ENSGALT00010067698.1
    Conserved Domains (2) summary
    COG0419
    Location:230 → 753
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:1583 → 1784
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  2. XM_040649271.2 → XP_040505205.1  CDK5 regulatory subunit-associated protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AGH3, A0A8V1AIB8
    Related
    ENSGALP00010041447.1, ENSGALT00010067704.1
    Conserved Domains (2) summary
    COG0419
    Location:230 → 753
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:1589 → 1823
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  3. XM_040649273.2 → XP_040505207.1  CDK5 regulatory subunit-associated protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8V1A6A0, A0A8V1AB60
    Related
    ENSGALP00010041445.1, ENSGALT00010067702.1
    Conserved Domains (2) summary
    COG0419
    Location:97 → 620
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:1456 → 1690
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  4. XM_040649274.2 → XP_040505208.1  CDK5 regulatory subunit-associated protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8V1AB60
    Conserved Domains (2) summary
    COG0419
    Location:1012 → 1546
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:112 → 474
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052589.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    4584202..4662679 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040685443.2 → XP_040541377.1  CDK5 regulatory subunit-associated protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8V1AGH3
    Conserved Domains (2) summary
    COG0419
    Location:394 → 1048
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:262 → 659
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  2. XM_040685442.2 → XP_040541376.1  CDK5 regulatory subunit-associated protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AGH3
    Conserved Domains (2) summary
    COG0419
    Location:1291 → 1825
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:262 → 659
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  3. XM_040685444.2 → XP_040541378.1  CDK5 regulatory subunit-associated protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8V1AB60
    Conserved Domains (2) summary
    COG0419
    Location:1158 → 1692
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:129 → 526
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  4. XM_040685445.2 → XP_040541379.1  CDK5 regulatory subunit-associated protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8V1AB60
    Conserved Domains (3) summary
    COG0419
    Location:1012 → 1546
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:1310 → 1544
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:14 → 368
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
Nucleotide Protein Strain
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