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ubc ubiquitin C [ Danio rerio (zebrafish) ]

Gene ID: 777766, updated on 4-Jan-2025

Summary

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Official Symbol
ubcprovided by ZNC
Official Full Name
ubiquitin Cprovided by ZNC
Primary source
ZFIN:ZDB-GENE-061110-88
See related
Ensembl:ENSDARG00000102632 AllianceGenome:ZFIN:ZDB-GENE-061110-88
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:7042025; wu:fb37h06; zgc:153686
Summary
Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination. Predicted to be active in cytoplasm and nucleus. Orthologous to human UBC (ubiquitin C). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See ubc in Genome Data Viewer
Location:
chromosome: 10
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (44692226..44694736)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (44845614..44848124)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene seizure related 6 homolog like Neighboring gene tyrosylprotein sulfotransferase 2 Neighboring gene scavenger receptor class B, member 1 Neighboring gene uncharacterized LOC137496616 Neighboring gene tachykinin receptor 1b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Characterization and biological function analysis of the trim3a gene from zebrafish (Danio rerio). Zhang X, et al. Fish Shellfish Immunol, 2012 May. PMID 22300786
  2. RNA secondary structure profiling in zebrafish reveals unique regulatory features. Kaushik K, et al. BMC Genomics, 2018 Feb 15. PMID 29448945, Free PMC Article
  3. An optimized QF-binary expression system for use in zebrafish. Burgess J, et al. Dev Biol, 2020 Sep 15. PMID 32697972
  4. A 3D Searchable Database of Transgenic Zebrafish Gal4 and Cre Lines for Functional Neuroanatomy Studies. Marquart GD, et al. Front Neural Circuits, 2015. PMID 26635538, Free PMC Article
  5. Structural basis for specific cleavage of Lys6-linked polyubiquitin chains by USP30. Sato Y, et al. Nat Struct Mol Biol, 2017 Nov. PMID 28945247

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables protein tag activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin protein ligase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in modification-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
polyubiquitin-C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077804.2 → NP_001071272.2  polyubiquitin-C

    Status: VALIDATED

    Source sequence(s)
    CU463283
    UniProtKB/TrEMBL
    A0A8M1NAS3, F1QHN6, Q6IS68
    Related
    ENSDARP00000139647.1, ENSDART00000157458.2
    Conserved Domains (2) summary
    cd01803
    Location:77 → 152
    Ubiquitin; Ubiquitin
    smart00213
    Location:1 → 72
    UBQ; Ubiquitin homologues

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    44692226..44694736
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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