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amt.L aminomethyltransferase L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 779328, updated on 27-Dec-2024

Summary

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Official Symbol
amt.L
Official Full Name
aminomethyltransferase L homeolog
Primary source
Xenbase:XB-GENE-921605
Locus tag
XELAEV_18023804mg
See related
EnsemblRapid:ENSXLAG00005029964 AllianceGenome:Xenbase:XB-GENE-921605
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
amt
Summary
Predicted to enable aminomethyltransferase activity and transaminase activity. Predicted to act upstream of or within glycine catabolic process. Predicted to be located in mitochondrion. Predicted to be part of glycine cleavage complex. Human ortholog(s) of this gene implicated in glycine encephalopathy and glycine encephalopathy 2. Orthologous to human AMT (aminomethyltransferase). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See amt.L in Genome Data Viewer
Location:
chromosome: 4L
Exon count:
9
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (124647563..124661572, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (119385948..119400065, complement)

Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene glutathione peroxidase 1 L homeolog Neighboring gene ras homolog family member A L homeolog Neighboring gene nicolin 1 L homeolog Neighboring gene acylaminoacyl-peptide hydrolase L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC154901

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables aminomethyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transaminase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within glycine catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of glycine cleavage complex IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
aminomethyltransferase L homeolog
Names
aminomethyltransferase (glycine cleavage system protein T)
NP_001090416.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001096947.1 → NP_001090416.1  aminomethyltransferase L homeolog

    See identical proteins and their annotated locations for NP_001090416.1

    Status: PROVISIONAL

    Source sequence(s)
    BC123373
    UniProtKB/TrEMBL
    A0A974D5Q8, Q0IH11
    Related
    ENSXLAP00005089625.1, ENSXLAT00005091296.1
    Conserved Domains (3) summary
    PLN02319
    Location:11 → 401
    PLN02319; aminomethyltransferase
    pfam01571
    Location:40 → 292
    GCV_T; Aminomethyltransferase folate-binding domain
    pfam08669
    Location:302 → 393
    GCV_T_C; Glycine cleavage T-protein C-terminal barrel domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    124647563..124661572 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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