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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_016195.1Â RefSeqGene
- Range
-
4748..407881
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_381
mRNA and Protein(s)
-
NM_000724.4 → NP_000715.2  voltage-dependent L-type calcium channel subunit beta-2 isoform 1
See identical proteins and their annotated locations for NP_000715.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents use of an alternate promoter and therefore differs in the 5' UTR and 5' coding region, compared to variant 2. These differences cause translation initiation at an alternate start codon, and result in an isoform (1) with a shorter and distinct N-terminus, compared to isoform 2.
- Source sequence(s)
-
AB208917, AL390783, AL450384
- Consensus CDS
-
CCDS7128.1
- UniProtKB/TrEMBL
-
Q59H42
- Related
- ENSP00000379821.2, ENST00000396576.6
- Conserved Domains (4) summary
-
- cd12040
Location:57 → 125
- SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
- pfam12052
Location:17 → 58
- VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
- pfam12782
Location:483 → 576
- Innate_immun; Invertebrate innate immunity transcript family
- cl27059
Location:225 → 405
- Guanylate_kin; Guanylate kinase
-
NM_001167945.2 → NP_001161417.1  voltage-dependent L-type calcium channel subunit beta-2 isoform 9
See identical proteins and their annotated locations for NP_001161417.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (9) uses an alternate 5' terminal exon, lacks an alternate in-frame exon and contains an alternate in-frame exon in the 5' coding region, compared to variant 2. These differences cause translation initiation at an alternate start codon, and result in an isoform (9) with a shorter and distinct N-terminus, compared to isoform 2.
- Source sequence(s)
-
AK307526, AL360231, AL450384
- UniProtKB/TrEMBL
-
A0A2R8Y555
- Related
- ENSP00000494209.2, ENST00000643096.2
- Conserved Domains (3) summary
-
- cd12040
Location:84 → 152
- SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
- pfam00625
Location:214 → 394
- Guanylate_kin; Guanylate kinase
- pfam12052
Location:44 → 85
- VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
-
NM_001330060.2 → NP_001316989.1  voltage-dependent L-type calcium channel subunit beta-2 isoform 10
Status: REVIEWED
- Description
- Transcript Variant: This variant (10) represents use of an alternate promoter, differs in the 5' UTR and 5' coding region, and uses an alternate internal in-frame exon compared to variant 2. These differences cause translation initiation at an alternate start codon and result in an isoform (10) that is shorter and has a distinct N-terminus compared to isoform 2.
- Source sequence(s)
-
AF465485, AL390783, AL450384, BP311576
- Consensus CDS
-
CCDS81442.1
- UniProtKB/TrEMBL
-
A0A087WVX5
- Related
- ENSP00000366536.3, ENST00000377319.9
- Conserved Domains (4) summary
-
- cd12040
Location:57 → 125
- SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
- pfam12052
Location:17 → 58
- VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
- pfam12782
Location:445 → 538
- Innate_immun; Invertebrate innate immunity transcript family
- cl27059
Location:187 → 367
- Guanylate_kin; Guanylate kinase
-
NM_001410882.1 → NP_001397811.1  voltage-dependent L-type calcium channel subunit beta-2 isoform 11
Status: REVIEWED
- Source sequence(s)
-
AL139814, AL450364, AL450384
- Consensus CDS
-
CCDS91220.1
- UniProtKB/TrEMBL
-
A0A494C0B2
- Related
- ENSP00000498460.1, ENST00000650685.1
-
NM_201570.3 → NP_963864.1  voltage-dependent L-type calcium channel subunit beta-2 isoform 7
See identical proteins and their annotated locations for NP_963864.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) represents use of an alternate promoter and therefore differs in the 5' UTR and 5' coding region, compared to variant 2. These differences cause translation initiation at an alternate start codon, and result in an isoform (7) with a shorter and distinct N-terminus, compared to isoform 2.
- Source sequence(s)
-
AF423192, AL139814, AL450384
- Consensus CDS
-
CCDS7129.1
- UniProtKB/TrEMBL
- B7Z1U5, Q5VVH1
- Related
- ENSP00000366532.4, ENST00000377315.6
- Conserved Domains (4) summary
-
- cd12040
Location:64 → 132
- SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
- pfam00625
Location:232 → 412
- Guanylate_kin; Guanylate kinase
- pfam12052
Location:24 → 65
- VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
- pfam12782
Location:490 → 583
- Innate_immun; Invertebrate innate immunity transcript family
-
NM_201571.4 → NP_963865.2  voltage-dependent L-type calcium channel subunit beta-2 isoform 6
See identical proteins and their annotated locations for NP_963865.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) uses an alternate 5' terminal exon and therefore differs in the 5' UTR and 5' coding region, compared to variant 2. These differences cause translation initiation at an alternate start codon, and result in an isoform (6) with a shorter and distinct N-terminus, compared to isoform 2.
- Source sequence(s)
-
AF423190, AL360231, AL450384, DC307859, DC352526
- Consensus CDS
-
CCDS7127.1
- UniProtKB/TrEMBL
-
B7Z3Y0
- Related
- ENSP00000282343.8, ENST00000282343.13
- Conserved Domains (3) summary
-
- cd12040
Location:84 → 152
- SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
- pfam00625
Location:252 → 432
- Guanylate_kin; Guanylate kinase
- pfam12052
Location:44 → 85
- VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
-
NM_201572.4 → NP_963866.2  voltage-dependent L-type calcium channel subunit beta-2 isoform 8
See identical proteins and their annotated locations for NP_963866.2
Status: REVIEWED
- Description
- Transcript Variant:This variant (8) uses an alternate 5' terminal exon, lacks an alternate in-frame exon and contains an alternate in-frame exon in the 5' coding region, compared to variant 2. These differences cause translation initiation at an alternate start codon, and result in an isoform (8) with a shorter and distinct N-terminus, compared to isoform 2.
- Source sequence(s)
-
AL360231, AL450384, AY393861, DC307859, DC352526
- Consensus CDS
-
CCDS41493.1
- UniProtKB/TrEMBL
-
A0A2R8Y555
- Related
- ENSP00000496203.1, ENST00000645287.2
- Conserved Domains (4) summary
-
- cd12040
Location:84 → 152
- SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
- pfam12052
Location:44 → 85
- VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
- pfam12782
Location:486 → 579
- Innate_immun; Invertebrate innate immunity transcript family
- cl27059
Location:228 → 408
- Guanylate_kin; Guanylate kinase
-
NM_201590.3 → NP_963884.2  voltage-dependent L-type calcium channel subunit beta-2 isoform 3
See identical proteins and their annotated locations for NP_963884.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) represents use of an alternate promoter and therefore differs in the 5' UTR and 5' coding region, compared to variant 2. These differences cause translation initiation at an alternate start codon, and result in an isoform (3) with a shorter and distinct N-terminus, compared to isoform 2.
- Source sequence(s)
-
AL450384, AY393859, DB235418
- Consensus CDS
-
CCDS41494.1
- UniProtKB/TrEMBL
-
Q59H42
- Related
- ENSP00000366546.4, ENST00000377329.10
- Conserved Domains (4) summary
-
- cd12040
Location:58 → 126
- SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
- pfam12052
Location:18 → 59
- VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
- pfam12782
Location:484 → 577
- Innate_immun; Invertebrate innate immunity transcript family
- cl27059
Location:226 → 406
- Guanylate_kin; Guanylate kinase
-
NM_201593.3 → NP_963887.2  voltage-dependent L-type calcium channel subunit beta-2 isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks an alternate in-frame exon and contains an alternate in-frame exon, in the 5' coding region, compared to variant 2. The encoded isoform (5) is shorter than isoform 2.
- Source sequence(s)
-
AF465485, AL119895, AL360231, AL450384, S60415
- UniProtKB/TrEMBL
-
A0A2R8Y555
- Conserved Domains (4) summary
-
- cd12040
Location:112 → 180
- SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
- pfam00625
Location:242 → 422
- Guanylate_kin; Guanylate kinase
- pfam12052
Location:72 → 113
- VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
- cl17190
Location:252 → 423
- NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
-
NM_201596.3 → NP_963890.2  voltage-dependent L-type calcium channel subunit beta-2 isoform 2
See identical proteins and their annotated locations for NP_963890.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) encodes the longest isoform (2).
- Source sequence(s)
-
AL360231, AL450384, S60415
- Consensus CDS
-
CCDS7125.1
- UniProtKB/Swiss-Prot
- A6PVM5, A6PVM7, A6PVM8, O00304, Q08289, Q5QJ99, Q5QJA0, Q5VVG9, Q5VVH0, Q5VWV6, Q6TME1, Q6TME2, Q6TME3, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341
- UniProtKB/TrEMBL
-
B7Z3Y0
- Related
- ENSP00000320025.8, ENST00000324631.13
- Conserved Domains (4) summary
-
- cd12040
Location:112 → 180
- SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
- pfam00625
Location:280 → 460
- Guanylate_kin; Guanylate kinase
- pfam12052
Location:72 → 113
- VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
- cl17190
Location:290 → 461
- NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
-
NM_201597.3 → NP_963891.1  voltage-dependent L-type calcium channel subunit beta-2 isoform 4
See identical proteins and their annotated locations for NP_963891.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks an alternate in-frame exon and contains an alternate in-frame exon, in the 5' coding region, compared to variant 2. The encoded isoform (4) is shorter than isoform 2.
- Source sequence(s)
-
AL360231, AL450384, AY393860, S60415
- Consensus CDS
-
CCDS7126.1
- UniProtKB/TrEMBL
-
B7Z3Y0
- Related
- ENSP00000344474.6, ENST00000352115.10
- Conserved Domains (4) summary
-
- cd12040
Location:112 → 180
- SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
- pfam00625
Location:256 → 436
- Guanylate_kin; Guanylate kinase
- pfam12052
Location:72 → 113
- VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
- cl17190
Location:266 → 437
- NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...