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dda1 DET1 and DDB1 associated 1 [ Danio rerio (zebrafish) ]

Gene ID: 796589, updated on 4-Jan-2025

Summary

Official Symbol
dda1provided by ZNC
Official Full Name
DET1 and DDB1 associated 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2137
See related
Ensembl:ENSDARG00000076074 AllianceGenome:ZFIN:ZDB-GENE-040426-2137
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:64154; wu:fa11a03; wu:fb73f11
Summary
Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process and protein polyubiquitination. Predicted to act upstream of or within regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Orthologous to human DDA1 (DET1 and DDB1 associated 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See dda1 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (5945867..5953633, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (5948614..5956403, complement)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein S15 Neighboring gene abhydrolase domain containing 8b Neighboring gene anoctamin 8b Neighboring gene GTP binding protein 3, mitochondrial

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC64154, MGC174517

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
part_of Cul4-RING E3 ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of Cul4-RING E3 ubiquitin ligase complex ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
DET1- and DDB1-associated protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213127.1NP_998292.1  DET1- and DDB1-associated protein 1

    See identical proteins and their annotated locations for NP_998292.1

    Status: PROVISIONAL

    Source sequence(s)
    BC054628
    UniProtKB/Swiss-Prot
    Q7T2A3
    UniProtKB/TrEMBL
    A9JT50
    Related
    ENSDARP00000112315.2, ENSDART00000123601.4
    Conserved Domains (1) summary
    pfam10172
    Location:567
    DDA1; Det1 complexing ubiquitin ligase

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    5945867..5953633 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005155700.5XP_005155757.1  DET1- and DDB1-associated protein 1 isoform X1

    See identical proteins and their annotated locations for XP_005155757.1

    UniProtKB/Swiss-Prot
    Q7T2A3
    UniProtKB/TrEMBL
    A9JT50
    Related
    ENSDARP00000119610.1, ENSDART00000140960.2
    Conserved Domains (1) summary
    pfam10172
    Location:567
    DDA1; Det1 complexing ubiquitin ligase

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394801.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    140176..147870 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)