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PF3D7_1452000 rhoptry neck protein 2 [ Plasmodium falciparum 3D7 ]

Gene ID: 812077, updated on 12-Sep-2024

Summary

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Gene symbol
PF3D7_1452000
Gene description
rhoptry neck protein 2
Locus tag
PF3D7_1452000
See related
PlasmoDB:PF3D7_1452000; VEuPathDB:PF3D7_1452000
Gene type
protein coding
RNA name
rhoptry neck protein 2
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
Orthologs
all
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Genomic context

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See PF3D7_1452000 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
1
Sequence:
Chromosome: 14; NC_037283.1 (2134298..2140867)

Chromosome 14 - NC_037283.1Genomic Context describing neighboring genes Neighboring gene sortilin Neighboring gene ribosome biogenesis protein TSR1, putative Neighboring gene leucine-rich repeat protein Neighboring gene aminomethyltransferase, putative

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037283.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Stability of the Plasmodium falciparum AMA1-RON2 Complex Is Governed by the Domain II (DII) Loop. Delgadillo RF, et al. PLoS One, 2016. PMID 26731670, Free PMC Article
  2. Immunization with a functional protein complex required for erythrocyte invasion protects against lethal malaria. Srinivasan P, et al. Proc Natl Acad Sci U S A, 2014 Jul 15. PMID 24958881, Free PMC Article
  3. Structural and functional insights into the malaria parasite moving junction complex. Vulliez-Le Normand B, et al. PLoS Pathog, 2012. PMID 22737069, Free PMC Article
  4. Rhoptry neck protein RON2 forms a complex with microneme protein AMA1 in Plasmodium falciparum merozoites. Cao J, et al. Parasitol Int, 2009 Mar. PMID 18952195
  5. Detection of the Rhoptry Neck Protein Complex in Plasmodium Sporozoites and Its Contribution to Sporozoite Invasion of Salivary Glands. Nozaki M, et al. mSphere, 2020 Aug 19. PMID 32817376, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 PubMed 
located_in rhoptry neck IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
rhoptry neck protein 2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_037283.1 Reference assembly

    Range
    2134298..2140867
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001348633.1 → XP_001348669.1  rhoptry neck protein 2 [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_001348669.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2I0C357, Q8IKV6, W7JN44
    Conserved Domains (2) summary
    PTZ00395
    Location:227 → 463
    PTZ00395; Sec24-related protein; Provisional
    NF033845
    Location:721 → 881
    MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
Nucleotide Protein
Heading Accession and Version

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