CR88 Chaperone protein htpG family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

Go to the top of the page Help

Official Symbol: CR88
Official Full Name: Chaperone protein htpG family protein
Primary source: TAIR:AT2G04030
Locus tag: AT2G04030
See related: Araport:AT2G04030
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AtHsp90.5; AtHsp90C; EMB1956; EMBRYO DEFECTIVE 1956; F3C11.14; F3C11_14; HEAT SHOCK PROTEIN 88.1; HEAT SHOCK PROTEIN 90.5; Hsp88.1; HSP90.5
Summary: Encodes a chloroplast-targeted 90-kDa heat shock protein located in the stroma involved in red-light mediated deetiolation response and crucial for protein import into the chloroplast stroma. Mutants are resistant to chlorate, have elongated hypocotyls in light, and affect the expression of NR2, CAB, and RBCS but NOT NR1 and NiR.
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See CR88 in Genome Data Viewer

Location:: chromosome: 2

Exon count:: 19

Sequence:: Chromosome: 2; NC_003071.7 (1281754..1286144)

Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

AtHsp90.5 may help in the disassembly of VIPP1 for thylakoid membrane formation and/or maintenance.
Title: Chloroplast-targeted Hsp90 plays essential roles in plastid development and embryogenesis in Arabidopsis possibly linking with VIPP1.
Results show that the induction expression of ABA-responsive genes under salt and drought stress was delayed by constitutive overexpression of cytosolic AtHsp90.2, but was hardly affected by that of organellar AtHsp90.5 and AtHsp90.7.
Title: Overexpression of AtHsp90.2, AtHsp90.5 and AtHsp90.7 in Arabidopsis thaliana enhances plant sensitivity to salt and drought stresses.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Homology

Orthologs from OrthoDB

NM_126439.4

Supported by ESTs:

NM_179601.1

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables ATP binding	HDA more info	PubMed
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables ATP-dependent protein folding chaperone	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein homodimerization activity	IDA Inferred from Direct Assay more info	PubMed
enables unfolded protein binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within de-etiolation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within embryo development ending in seed dormancy	NAS Non-traceable Author Statement more info
involved_in protein folding	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein import into chloroplast stroma	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to chlorate	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to heat	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to salt stress	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to water deprivation	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	HDA more info	PubMed
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in chloroplast envelope	HDA more info	PubMed
located_in chloroplast stroma	HDA more info	PubMed
located_in chloroplast stroma	IDA Inferred from Direct Assay more info	PubMed
NOT located_in cytosol	RCA inferred from Reviewed Computational Analysis more info	PubMed
located_in mitochondrion	HDA more info	PubMed
located_in plant-type vacuole	HDA more info	PubMed
located_in plastid	HDA more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: Chaperone protein htpG family protein

NP_178487.1

CR88; FUNCTIONS IN: ATP binding; INVOLVED IN: in 7 processes; LOCATED IN: mitochondrion, plasma membrane, chloroplast stroma, chloroplast, chloroplast envelope; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Chaperone protein htpG (InterPro:IPR001404), Heat shock protein Hsp90, conserved site (InterPro:IPR019805), Heat shock protein Hsp90, C-terminal (InterPro:IPR020576), Heat shock protein Hsp90, N-terminal (InterPro:IPR020575), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), ATPase-like, ATP-binding domain (InterPro:IPR003594); BEST Arabidopsis thaliana protein match is: HEAT SHOCK PROTEIN 89.1 (TAIR:AT3G07770.1); Has 8928 Blast hits to 8878 proteins in 2458 species: Archae - 4; Bacteria - 3413; Metazoa - 2083; Fungi - 313; Plants - 465; Viruses - 0; Other Eukaryotes - 2650 (source: NCBI BLink).

NP_849932.1

CR88; FUNCTIONS IN: ATP binding; INVOLVED IN: in 7 processes; LOCATED IN: mitochondrion, chloroplast stroma, plasma membrane, chloroplast, chloroplast envelope; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Chaperone protein htpG (InterPro:IPR001404), Heat shock protein Hsp90, conserved site (InterPro:IPR019805), Heat shock protein Hsp90, C-terminal (InterPro:IPR020576), Heat shock protein Hsp90, N-terminal (InterPro:IPR020575), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), ATPase-like, ATP-binding domain (InterPro:IPR003594); BEST Arabidopsis thaliana protein match is: HEAT SHOCK PROTEIN 89.1 (TAIR:AT3G07770.1); Has 8908 Blast hits to 8859 proteins in 2447 species: Archae - 4; Bacteria - 3393; Metazoa - 2086; Fungi - 314; Plants - 461; Viruses - 0; Other Eukaryotes - 2650 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003071.7 Reference assembly

Range

1281754..1286144

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_126439.4 → NP_178487.1 Chaperone protein htpG family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_178487.1

Status: REVIEWED

UniProtKB/Swiss-Prot

F4IU89, Q0WMQ3, Q0WMV4, Q8LPS0, Q9SIF2

UniProtKB/TrEMBL

A0A178VPV7, A0A5S9WWZ5, O23638

Conserved Domains (1) summary

PRK05218
Location:77 → 738

PRK05218; heat shock protein 90; Provisional
NM_179601.1 → NP_849932.1 Chaperone protein htpG family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_849932.1

Status: REVIEWED

UniProtKB/TrEMBL

O23638

Conserved Domains (3) summary

PRK05218
Location:77 → 735

PRK05218; heat shock protein 90; Provisional

pfam00183
Location:264 → 765

HSP90; Hsp90 protein

pfam02518
Location:104 → 210

HATPase_c; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase