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Disease resistance protein (TIR-NBS-LRR class) family [ Arabidopsis thaliana (thale cress) ]

Gene ID: 815893, updated on 18-Sep-2024

Summary

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Official Full Name
Disease resistance protein (TIR-NBS-LRR class) family
Primary source
TAIR:AT2G14080
Locus tag
AT2G14080
See related
Araport:AT2G14080
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
T22C12.1
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Genomic context

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Location:
chromosome: 2
Exon count:
4
Sequence:
Chromosome: 2; NC_003071.7 (5925119..5929902)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene wound-responsive protein-like protein Neighboring gene miscRNA Neighboring gene uncharacterized protein Neighboring gene cytochrome P450, family 705, subfamily A, polypeptide 13

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

General gene information

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NM_001335412.1
NM_126980.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ADP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Disease resistance protein (TIR-NBS-LRR class) family
NP_179024.1
  • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: signal transduction, apoptosis, defense response, innate immune response; LOCATED IN: intrinsic to membrane, endomembrane system; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Disease resistance protein (InterPro:IPR000767), Toll-Interleukin receptor (InterPro:IPR000157); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) (TAIR:AT5G11250.1); Has 59112 Blast hits to 27121 proteins in 1046 species: Archae - 26; Bacteria - 3020; Metazoa - 5754; Fungi - 417; Plants - 46550; Viruses - 22; Other Eukaryotes - 3323 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    5925119..5929902
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_126980.3 → NP_179024.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_179024.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4IFF6, Q8S8G3
    Conserved Domains (7) summary
    cd00009
    Location:256 → 374
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    cd09293
    Location:674 → 830
    AMN1; Antagonist of mitotic exit network protein 1
    PLN03210
    Location:52 → 1115
    PLN03210; Resistant to P. syringae 6; Provisional
    sd00033
    Location:653 → 675
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:631 → 650
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam01582
    Location:56 → 221
    TIR; TIR domain
    pfam07725
    Location:652 → 671
    LRR_3; Leucine Rich Repeat

  2. NM_001335412.1 → NP_001323706.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AXZ9
Nucleotide Protein
Heading Accession and Version

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