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Disease resistance protein (TIR-NBS-LRR class) family [ Arabidopsis thaliana (thale cress) ]

Gene ID: 816188, updated on 18-Sep-2024

Summary

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Official Full Name
Disease resistance protein (TIR-NBS-LRR class) family
Primary source
TAIR:AT2G16870
Locus tag
AT2G16870
See related
Araport:AT2G16870
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F12A24.5; F12A24_5
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Genomic context

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Location:
chromosome: 2
Exon count:
5
Sequence:
Chromosome: 2; NC_003071.7 (7307970..7311796, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene plasma membrane intrinsic protein 2;8 Neighboring gene GCIP-interacting family protein Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene UDP-Glycosyltransferase superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis scaffold protein RACK1A interacts with diverse environmental stress and photosynthesis related proteins. Kundu N, et al. Plant Signal Behav, 2013 May. PMID 23435172, Free PMC Article
  2. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
  3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

  • At2g16870_Arabidopsis_lyrata_ssp._lyrata_CAN1 (e-PCR)
  • At2g16870_Arabidopsis_lyrata_ssp._petraea_GER1 (e-PCR)

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ADP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in defense response IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
Disease resistance protein (TIR-NBS-LRR class) family
NP_179279.1
  • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: signal transduction, apoptosis, defense response, innate immune response; LOCATED IN: intrinsic to membrane; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT1G64070.1); Has 20392 Blast hits to 15740 proteins in 660 species: Archae - 17; Bacteria - 1396; Metazoa - 2110; Fungi - 75; Plants - 16264; Viruses - 0; Other Eukaryotes - 530 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    7307970..7311796 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001335494.1 → NP_001323734.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AXY0

  2. NM_001335495.1 → NP_001323733.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AXY0

  3. NM_127240.2 → NP_179279.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_179279.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A654EYI0, Q9ZVX6
    Conserved Domains (7) summary
    PLN03210
    Location:1 → 981
    PLN03210; Resistant to P. syringae 6; Provisional
    sd00031
    Location:552 → 594
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:602 → 624
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:807 → 836
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam01582
    Location:12 → 175
    TIR; TIR domain
    pfam07725
    Location:601 → 620
    LRR_3; Leucine Rich Repeat
    cl21455
    Location:213 → 325
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Nucleotide Protein
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