U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

RTNLB13 Reticulan like protein B13 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 816896, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
RTNLB13
Official Full Name
Reticulan like protein B13
Primary source
TAIR:AT2G23640
Locus tag
AT2G23640
See related
Araport:AT2G23640
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F26B6.29; Reticulan like protein B13
Summary
Encodes RTNLB13, a reticulon protein integral to the endoplasmic reticulum (ER) membrane that have the ability to shape the ER into tubules.
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See RTNLB13 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
4
Sequence:
Chromosome: 2; NC_003071.7 (10057542..10059108)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene SKU5 similar 16 Neighboring gene ncRNA Neighboring gene tRNA-Met Neighboring gene LOB domain-containing protein 10

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Curvature sensing amphipathic helix in the C-terminus of RTNLB13 is conserved in all endoplasmic reticulum shaping reticulons in Arabidopsis thaliana. Brooks RL, et al. Sci Rep, 2021 Mar 18. PMID 33737685, Free PMC Article
  2. Bacterial expression, purification and biophysical characterization of the smallest plant reticulon isoform, RTNLB13. Chow M, et al. Protein Expr Purif, 2018 Dec. PMID 29969670
  3. A C-terminal amphipathic helix is necessary for the in vivo tubule-shaping function of a plant reticulon. Breeze E, et al. Proc Natl Acad Sci U S A, 2016 Sep 27. PMID 27621477, Free PMC Article
  4. Transmembrane domain length is responsible for the ability of a plant reticulon to shape endoplasmic reticulum tubules in vivo. Tolley N, et al. Plant J, 2010 Nov. PMID 20969742
  5. Five Arabidopsis reticulon isoforms share endoplasmic reticulum location, topology, and membrane-shaping properties. Sparkes I, et al. Plant Cell, 2010 Apr. PMID 20424177, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Curvature sensing amphipathic helix in the C-terminus of RTNLB13 is conserved in all endoplasmic reticulum shaping reticulons in Arabidopsis thaliana.
    Title: Curvature sensing amphipathic helix in the C-terminus of RTNLB13 is conserved in all endoplasmic reticulum shaping reticulons in Arabidopsis thaliana.
  2. Bacterial expression, purification and molecular characterization of the smallest plant reticulon isoform, RTNLB13, has been reported.
    Title: Bacterial expression, purification and biophysical characterization of the smallest plant reticulon isoform, RTNLB13.
  3. the conserved amphipathic helix is a key structural feature for RTN13 function in vivo.[RTN13]
    Title: A C-terminal amphipathic helix is necessary for the in vivo tubule-shaping function of a plant reticulon.
  4. The length of the transmembrane regions is directly correlated with the ability of RTNLB13 to induce membrane tubulation.
    Title: Transmembrane domain length is responsible for the ability of a plant reticulon to shape endoplasmic reticulum tubules in vivo.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help
NM_127928.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within endoplasmic reticulum tubular network organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in endoplasmic reticulum tubular network organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasmic side of endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endoplasmic reticulum tubular network IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Reticulan like protein B13
NP_565555.1
  • Reticulan like protein B13 (RTNLB13); CONTAINS InterPro DOMAIN/s: Reticulon (InterPro:IPR003388); BEST Arabidopsis thaliana protein match is: Reticulon family protein (TAIR:AT3G10915.3); Has 751 Blast hits to 751 proteins in 54 species: Archae - 0; Bacteria - 0; Metazoa - 324; Fungi - 0; Plants - 418; Viruses - 0; Other Eukaryotes - 9 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    10057542..10059108
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_127928.3 → NP_565555.1  Reticulan like protein B13 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_565555.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O64837
    UniProtKB/TrEMBL
    A0A5S9X0W7
    Conserved Domains (1) summary
    pfam02453
    Location:16 → 170
    Reticulon; Reticulon
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O64837.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools