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CDC6 cell division control 6 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817518, updated on 18-Sep-2024

Summary

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Official Symbol
CDC6
Official Full Name
cell division control 6
Primary source
TAIR:AT2G29680
Locus tag
AT2G29680
See related
Araport:AT2G29680
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATCDC6; cell division control 6; T27A16.22; T27A16_22
Summary
Encodes cell division control protein 6 (CDC6).
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Genomic context

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See CDC6 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
16
Sequence:
Chromosome: 2; NC_003071.7 (12689171..12693121)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene zinc finger (C2H2 type) family protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene uncharacterized protein Neighboring gene anthranilate synthase 2 Neighboring gene pleckstrin homologue 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression and stability of Arabidopsis CDC6 are associated with endoreplication. Castellano MM, et al. Plant Cell, 2001 Dec. PMID 11752380, Free PMC Article
  2. DNA replication licensing affects cell proliferation or endoreplication in a cell type-specific manner. Castellano Mdel M, et al. Plant Cell, 2004 Sep. PMID 15316110, Free PMC Article
  3. Identification of kinase substrates by bimolecular complementation assays. Pusch S, et al. Plant J, 2012 Apr. PMID 22098373
  4. Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. Van Leene J, et al. Mol Syst Biol, 2010 Aug 10. PMID 20706207, Free PMC Article
  5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_128522.1
NM_179806.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA endoreduplication TAS
Traceable Author Statement
more info
 PubMed 
involved_in DNA replication initiation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
cell division control 6
NP_565686.1
  • cell division control 6 (CDC6); INVOLVED IN: regulation of cell cycle, DNA replication; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: CDC6, C-terminal (InterPro:IPR015163), Cell division control, Cdc6 (InterPro:IPR016314); BEST Arabidopsis thaliana protein match is: Cell division control, Cdc6 (TAIR:AT1G07270.1); Has 1212 Blast hits to 1203 proteins in 331 species: Archae - 284; Bacteria - 0; Metazoa - 344; Fungi - 285; Plants - 98; Viruses - 0; Other Eukaryotes - 201 (source: NCBI BLink).
NP_850137.1
  • cell division control 6 (CDC6); FUNCTIONS IN: ATP binding; INVOLVED IN: regulation of cell cycle, DNA replication; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA-type, core (InterPro:IPR003959), CDC6, C-terminal (InterPro:IPR015163), Cell division control, Cdc6 (InterPro:IPR016314); BEST Arabidopsis thaliana protein match is: Cell division control, Cdc6 (TAIR:AT1G07270.1); Has 1385 Blast hits to 1377 proteins in 339 species: Archae - 397; Bacteria - 0; Metazoa - 348; Fungi - 289; Plants - 116; Viruses - 0; Other Eukaryotes - 235 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    12689171..12693121
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_179806.2 → NP_850137.1  cell division control 6 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_850137.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9X2I3
    Conserved Domains (3) summary
    cd08768
    Location:411 → 493
    Cdc6_C; Winged-helix domain of essential DNA replication protein Cell division control protein (Cdc6), which mediates DNA binding
    COG1474
    Location:117 → 500
    CDC6; Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]
    pfam13401
    Location:152 → 287
    AAA_22; AAA domain

  2. NM_128522.1 → NP_565686.1  cell division control 6 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_565686.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O82387, Q94CM2, Q94G54
    UniProtKB/TrEMBL
    A0A5S9X2I3
    Conserved Domains (3) summary
    cd08768
    Location:442 → 524
    Cdc6_C; Winged-helix domain of essential DNA replication protein Cell division control protein (Cdc6), which mediates DNA binding
    COG1474
    Location:117 → 531
    CDC6; Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]
    pfam13401
    Location:152 → 281
    AAA_22; AAA domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O82387.2

Gene LinkOut

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