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CCT1 phosphorylcholine cytidylyltransferase [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817786, updated on 18-Sep-2024

Summary

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Official Symbol
CCT1
Official Full Name
phosphorylcholine cytidylyltransferase
Primary source
TAIR:AT2G32260
Locus tag
AT2G32260
See related
Araport:AT2G32260
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATCCT1; phosphorylcholine cytidylyltransferase; T32F6.22; T32F6_22
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Genomic context

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See CCT1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
7
Sequence:
Chromosome: 2; NC_003071.7 (13697457..13700648)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene early endosome antigen Neighboring gene FAR1-related sequence 2 Neighboring gene ncRNA Neighboring gene zinc transporter 3 precursor

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis CTP:phosphocholine cytidylyltransferase 1 is phosphorylated and inhibited by sucrose nonfermenting 1-related protein kinase 1 (SnRK1). Caldo KMP, et al. J Biol Chem, 2019 Oct 25. PMID 31439667, Free PMC Article
  2. Isozyme-specific modes of activation of CTP:phosphorylcholine cytidylyltransferase in Arabidopsis thaliana at low temperature. Inatsugi R, et al. Plant Cell Physiol, 2009 Oct. PMID 19667100
  3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. SnRK1 mediates the phosphorylation and concomitant inhibition of AtCCT1.
    Title: Arabidopsis CTP:phosphocholine cytidylyltransferase 1 is phosphorylated and inhibited by sucrose nonfermenting 1-related protein kinase 1 (SnRK1).
  2. The CDP-choline pathway of A. thaliana is up-regulated at low temperature via isogene-specific modes: enhanced expression of CCT2 and post-translational activation/inactivation of CCT1 in membranes.
    Title: Isozyme-specific modes of activation of CTP:phosphorylcholine cytidylyltransferase in Arabidopsis thaliana at low temperature.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

NM_001336383.1
NM_128785.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables choline-phosphate cytidylyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables choline-phosphate cytidylyltransferase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in CDP-choline pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phosphatidylcholine biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
phosphorylcholine cytidylyltransferase
NP_180785.1
  • phosphorylcholine cytidylyltransferase (CCT1); CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Cytidyltransferase-related (InterPro:IPR004821), Cytidylyltransferase (InterPro:IPR004820); BEST Arabidopsis thaliana protein match is: phosphorylcholine cytidylyltransferase2 (TAIR:AT4G15130.1); Has 2466 Blast hits to 2109 proteins in 632 species: Archae - 27; Bacteria - 791; Metazoa - 538; Fungi - 333; Plants - 250; Viruses - 5; Other Eukaryotes - 522 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    13697457..13700648
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_128785.3 → NP_180785.1  phosphorylcholine cytidylyltransferase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_180785.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9ZV56
    UniProtKB/TrEMBL
    A0A178VQG6, A0A2K8ETV8, A0A384KL63, Q42555
    Conserved Domains (1) summary
    PLN02413
    Location:26 → 293
    PLN02413; choline-phosphate cytidylyltransferase

  2. NM_001336383.1 → NP_001323485.1  phosphorylcholine cytidylyltransferase [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AXC2, Q42555
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9ZV56.1

Gene LinkOut

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