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GAMMA-TIP gamma tonoplast intrinsic protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 818255, updated on 18-Sep-2024

Summary

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Official Symbol
GAMMA-TIP
Official Full Name
gamma tonoplast intrinsic protein
Primary source
TAIR:AT2G36830
Locus tag
AT2G36830
See related
Araport:AT2G36830
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
gamma tonoplast intrinsic protein; GAMMA TONOPLAST INTRINSIC PROTEIN 1; GAMMA-TIP1; GAMMA-TONOPLAST INTRINSIC PROTEIN; T1J8.1; T1J8_1; TIP1;1; TONOPLAST INTRINSIC PROTEIN 1;1
Summary
Encodes a tonoplast intrinsic protein, which functions as water channel. It has also been shown to be able to facilitate the transport of urea and hydrogen peroxide. Highly expressed in vascular tissues of the root, stem, cauline leaves and flowers but not in the apical meristems.
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Genomic context

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See GAMMA-TIP in Genome Data Viewer
Location:
chromosome: 2
Exon count:
2
Sequence:
Chromosome: 2; NC_003071.7 (15445294..15446621)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene mid region of cactin Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ACT-like superfamily protein Neighboring gene glucan synthase-like 8 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The vacuolar membrane protein gamma-TIP creates water specific channels in Xenopus oocytes. Maurel C, et al. EMBO J, 1993 Jun. PMID 8508761, Free PMC Article
  2. A complex and mobile structure forms a distinct subregion within the continuous vacuolar membrane in young cotyledons of Arabidopsis. Saito C, et al. Plant J, 2002 Feb. PMID 11844103
  3. Life with and without AtTIP1;1, an Arabidopsis aquaporin preferentially localized in the apposing tonoplasts of adjacent vacuoles. Beebo A, et al. Plant Mol Biol, 2009 May. PMID 19229639
  4. The effects of the loss of TIP1;1 and TIP1;2 aquaporins in Arabidopsis thaliana. Schüssler MD, et al. Plant J, 2008 Dec. PMID 18643996
  5. Specific aquaporins facilitate the diffusion of hydrogen peroxide across membranes. Bienert GP, et al. J Biol Chem, 2007 Jan 12. PMID 17105724

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data show that the highly abundant tonoplast aquaporins (AQPs) isoforms AtTIP1;1, AtTIP1;2, and AtTIP2;1 facilitate the emergence of new lateral root primordia (LRPs).
    Title: Tonoplast Aquaporins Facilitate Lateral Root Emergence.
  2. TIP1;1 and TIP1;2 single or double mutants did not show significant changes in water content or water retention, and showed no sign of early senescence or growth retardation. [TIP1;1]
    Title: The effects of the loss of TIP1;1 and TIP1;2 aquaporins in Arabidopsis thaliana.
  3. unlike for TIP1;1, trafficking of markers for TIP3;1 and TIP2;1 is insensitive to Brefeldin A in Arabidopsis hypocotyls
    Title: A small molecule inhibitor partitions two distinct pathways for trafficking of tonoplast intrinsic proteins in Arabidopsis.
  4. AtTIP1;1 is present in multiple vacuolar compartments and is preferentially found in the apposing tonoplasts of adjacent vacuoles. AtTIP1;1 loss of function did not lead to early plant death.
    Title: Life with and without AtTIP1;1, an Arabidopsis aquaporin preferentially localized in the apposing tonoplasts of adjacent vacuoles.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

NM_129238.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables urea transmembrane transporter activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables water channel activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables water channel activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within gibberellic acid mediated signaling pathway TAS
Traceable Author Statement
more info
  
acts_upstream_of_or_within hydrogen peroxide transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within urea transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within water transport IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in central vacuole IDA
Inferred from Direct Assay
more info
 PubMed 
located_in chloroplast envelope HDA PubMed 
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in plant-type vacuole HDA PubMed 
located_in plant-type vacuole membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in protein storage vacuole IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
gamma tonoplast intrinsic protein
NP_181221.1
  • gamma tonoplast intrinsic protein (GAMMA-TIP); FUNCTIONS IN: water channel activity, urea transmembrane transporter activity; INVOLVED IN: in 6 processes; LOCATED IN: in 7 components; EXPRESSED IN: 33 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Major intrinsic protein, conserved site (InterPro:IPR022357), Aquaporin (InterPro:IPR012269), Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: tonoplast intrinsic protein 2 (TAIR:AT3G26520.1); Has 11016 Blast hits to 10983 proteins in 2213 species: Archae - 82; Bacteria - 5238; Metazoa - 1501; Fungi - 451; Plants - 2489; Viruses - 0; Other Eukaryotes - 1255 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    15445294..15446621
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_129238.4 → NP_181221.1  gamma tonoplast intrinsic protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_181221.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P21652, P25818, Q42075, Q8L5T8
    UniProtKB/TrEMBL
    A0A5S9X4N0, A0A654FA46
    Conserved Domains (1) summary
    PLN00027
    Location:1 → 251
    PLN00027; aquaporin TIP; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P25818.1

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