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CXIP2 CAX-interacting protein 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 818407, updated on 18-Sep-2024

Summary

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Official Symbol
CXIP2
Official Full Name
CAX-interacting protein 2
Primary source
TAIR:AT2G38270
Locus tag
AT2G38270
See related
Araport:AT2G38270
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATGRX2; AtGRXS16; CAX-interacting protein 2; F16M14.20; F16M14_20; GLUTAREDOXIN; glutaredoxin 16; GLUTAREDOXIN 2
Summary
Encodes protein homologous to CXIP1. CXIP1 is a PICOT domain containing protein interacts with CAX1, a high capacity calcium transporter. However, CXP2 does not interact with CAX1 and only moderately activates another calcium transporter CAX4.
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Genomic context

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See CXIP2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
2
Sequence:
Chromosome: 2; NC_003071.7 (16031185..16033169, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene hypothetical protein (DUF239) Neighboring gene miscRNA Neighboring gene AMP deaminase, putative / myoadenylate deaminase Neighboring gene ammonium transporter 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The thioredoxin-mediated recycling of Arabidopsis thaliana GRXS16 relies on a conserved C-terminal cysteine. Zannini F, et al. Biochim Biophys Acta Gen Subj, 2019 Feb. PMID 30502392
  2. Involvement of Arabidopsis glutaredoxin S14 in the maintenance of chlorophyll content. Rey P, et al. Plant Cell Environ, 2017 Oct. PMID 28741719
  3. Cloning and characterization of CXIP1, a novel PICOT domain-containing Arabidopsis protein that associates with CAX1. Cheng NH, et al. J Biol Chem, 2003 Feb 21. PMID 12480930
  4. Monothiol glutaredoxin-BolA interactions: redox control of Arabidopsis thaliana BolA2 and SufE1. Couturier J, et al. Mol Plant, 2014 Jan. PMID 24203231
  5. Redox Conformation-Specific Protein-Protein Interactions of the 2-Cysteine Peroxiredoxin in Arabidopsis. Liebthal M, et al. Antioxidants (Basel), 2020 Jun 11. PMID 32545358, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_129383.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within monoatomic cation transport IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast stroma HDA PubMed 

General protein information

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Preferred Names
CAX-interacting protein 2
NP_565885.1
  • CAX-interacting protein 2 (CXIP2); FUNCTIONS IN: electron carrier activity, protein disulfide oxidoreductase activity; INVOLVED IN: cation transport; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Glutaredoxin (InterPro:IPR002109), Thioredoxin-like fold (InterPro:IPR012336), Glutaredoxin-related protein (InterPro:IPR004480); BEST Arabidopsis thaliana protein match is: CAX interacting protein 1 (TAIR:AT3G54900.1); Has 5833 Blast hits to 5648 proteins in 1292 species: Archae - 30; Bacteria - 2544; Metazoa - 528; Fungi - 278; Plants - 476; Viruses - 0; Other Eukaryotes - 1977 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    16031185..16033169 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_129383.3 → NP_565885.1  CAX-interacting protein 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_565885.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O80451, Q8H7F6, Q8LD13
    UniProtKB/TrEMBL
    A0A178VW24, A0A5S9X547, A0A7G2ECH3
    Conserved Domains (2) summary
    cd10457
    Location:88 → 161
    GIY-YIG_AtGrxS16; GIY-YIG domain found in CAXIP1-like proteins
    cd03028
    Location:197 → 289
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8H7F6.2

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