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PPC2 phosphoenolpyruvate carboxylase 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 818860, updated on 18-Sep-2024

Summary

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Official Symbol
PPC2
Official Full Name
phosphoenolpyruvate carboxylase 2
Primary source
TAIR:AT2G42600
Locus tag
AT2G42600
See related
Araport:AT2G42600
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATPPC2; F14N22.13; F14N22_13; phosphoenolpyruvate carboxylase 2
Summary
Encodes one of four Arabidopsis phosphoenolpyruvate carboxylase proteins.
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Genomic context

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See PPC2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
11
Sequence:
Chromosome: 2; NC_003071.7 (17734302..17739167, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene TRICHOME BIREFRINGENCE-LIKE 39 Neighboring gene tetratricopetide-repeat thioredoxin-like 3 Neighboring gene general regulatory factor 9 Neighboring gene LIGHT-DEPENDENT SHORT HYPOCOTYLS-like protein (DUF640) Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phosphoenolpyruvate Carboxylase in Arabidopsis Leaves Plays a Crucial Role in Carbon and Nitrogen Metabolism. Shi J, et al. Plant Physiol, 2015 Mar. PMID 25588735, Free PMC Article
  2. Phosphoenolpyruvate carboxylase (PEPC) and PEPC-kinase (PEPC-k) isoenzymes in Arabidopsis thaliana: role in control and abiotic stress conditions. Feria AB, et al. Planta, 2016 Oct. PMID 27306451
  3. Tandem affinity purification and mass spectrometric analysis of ubiquitylated proteins in Arabidopsis. Saracco SA, et al. Plant J, 2009 Jul. PMID 19292762, Free PMC Article
  4. Redox Conformation-Specific Protein-Protein Interactions of the 2-Cysteine Peroxiredoxin in Arabidopsis. Liebthal M, et al. Antioxidants (Basel), 2020 Jun 11. PMID 32545358, Free PMC Article
  5. Hydroponic isotope labelling of entire plants (HILEP) for quantitative plant proteomics; an oxidative stress case study. Bindschedler LV, et al. Phytochemistry, 2008 Jul. PMID 18538804

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Phosphoenolpyruvate carboxylase (PEPC) activity was decreased in shoots and roots of ppc2 and ppc3 mutants, and phosphate starvation increased the expression of all PEPC and phosphoenolpyruvate carboxylase kinase genes in shoots, but only PPC3 and PPCK2 in roots.
    Title: Phosphoenolpyruvate carboxylase (PEPC) and PEPC-kinase (PEPC-k) isoenzymes in Arabidopsis thaliana: role in control and abiotic stress conditions.
  2. PEPC in leaves plays a crucial role in modulating the balance of carbon and nitrogen metabolism in Arabidopsis.
    Title: Phosphoenolpyruvate Carboxylase in Arabidopsis Leaves Plays a Crucial Role in Carbon and Nitrogen Metabolism.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001336987.1
NM_180041.5
NM_180042.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables phosphoenolpyruvate carboxylase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within leaf development IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in apoplast HDA PubMed 
located_in chloroplast HDA PubMed 
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in cytosol HDA PubMed 
located_in plasmodesma HDA PubMed 

General protein information

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Preferred Names
phosphoenolpyruvate carboxylase 2
NP_850372.4
  • phosphoenolpyruvate carboxylase 2 (PPC2); FUNCTIONS IN: phosphoenolpyruvate carboxylase activity, catalytic activity; INVOLVED IN: tricarboxylic acid cycle; LOCATED IN: cytosol, apoplast, chloroplast, plasma membrane; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pyruvate/Phosphoenolpyruvate kinase, catalytic core (InterPro:IPR015813), Phosphoenolpyruvate carboxylase, active site (InterPro:IPR018129), Phosphoenolpyruvate carboxylase (InterPro:IPR001449), Phosphoenolpyruvate carboxylase, C-terminal region (InterPro:IPR021135); BEST Arabidopsis thaliana protein match is: phosphoenolpyruvate carboxylase 1 (TAIR:AT1G53310.3); Has 6860 Blast hits to 6799 proteins in 1908 species: Archae - 27; Bacteria - 2656; Metazoa - 4; Fungi - 0; Plants - 1774; Viruses - 0; Other Eukaryotes - 2399 (source: NCBI BLink).
NP_850373.4
  • phosphoenolpyruvate carboxylase 2 (PPC2); FUNCTIONS IN: phosphoenolpyruvate carboxylase activity, catalytic activity; INVOLVED IN: tricarboxylic acid cycle; LOCATED IN: cytosol, apoplast, chloroplast, plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pyruvate/Phosphoenolpyruvate kinase, catalytic core (InterPro:IPR015813), Phosphoenolpyruvate carboxylase, active site (InterPro:IPR018129), Phosphoenolpyruvate carboxylase (InterPro:IPR001449), Phosphoenolpyruvate carboxylase, C-terminal region (InterPro:IPR021135); BEST Arabidopsis thaliana protein match is: phosphoenolpyruvate carboxylase 1 (TAIR:AT1G53310.3); Has 6860 Blast hits to 6799 proteins in 1908 species: Archae - 27; Bacteria - 2656; Metazoa - 4; Fungi - 0; Plants - 1774; Viruses - 0; Other Eukaryotes - 2399 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    17734302..17739167 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_180041.5 → NP_850372.4  phosphoenolpyruvate carboxylase 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_850372.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q5GM68, Q8GVE9, Q9SIN0
    UniProtKB/TrEMBL
    A0A178VV64, A0A5S9X6E1
    Conserved Domains (1) summary
    pfam00311
    Location:163 → 963
    PEPcase; Phosphoenolpyruvate carboxylase

  2. NM_001336987.1 → NP_001324501.1  phosphoenolpyruvate carboxylase 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q5GM68, Q8GVE9, Q9SIN0
    UniProtKB/TrEMBL
    A0A178VV64, A0A5S9X6E1
    Conserved Domains (1) summary
    pfam00311
    Location:163 → 963
    PEPcase; Phosphoenolpyruvate carboxylase

  3. NM_180042.5 → NP_850373.4  phosphoenolpyruvate carboxylase 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_850373.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q5GM68, Q8GVE9, Q9SIN0
    UniProtKB/TrEMBL
    A0A178VV64, A0A5S9X6E1
    Conserved Domains (1) summary
    pfam00311
    Location:163 → 963
    PEPcase; Phosphoenolpyruvate carboxylase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5GM68.2

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