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ML2 MEI2-like 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 818890, updated on 18-Sep-2024

Summary

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Official Symbol
ML2
Official Full Name
MEI2-like 2
Primary source
TAIR:AT2G42890
Locus tag
AT2G42890
See related
Araport:AT2G42890
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AML2; F7D19.11; F7D19_11; MEI2-like 2
Summary
A member of mei2-like gene family, predominantly plant-based family of genes encoding RNA binding proteins with characteristic presence of a highly conserved RNA binding motif first described in the mei2 gene of the fission yeast S. pombe. In silico analyses reveal nine mei2 -like genes in A. thaliana. They were grouped into four distinct clades, based on overall sequence similarity and subfamily-specific sequence elements. AML2 is a member of two sister clades of mei2-like gene family, AML1 through AML5, and belongs to the clade named ALM235. AML2 is expressed during early embryo development (heart and torpedo stage) and predominantly in vegetative organs; no significant accumulation was detected in floral apices.
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Genomic context

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See ML2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
13
Sequence:
Chromosome: 2; NC_003071.7 (17849819..17854553)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene MAP kinase 20 Neighboring gene Defensin-like (DEFL) family protein Neighboring gene Plant basic secretory protein (BSP) family protein Neighboring gene Phosphoribosyltransferase family protein Neighboring gene Pentatricopeptide repeat (PPR-like) superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Arabidopsis-mei2-like genes play a role in meiosis and vegetative growth in Arabidopsis. Kaur J, et al. Plant Cell, 2006 Mar. PMID 16473967, Free PMC Article
  2. PLASTOCHRON2 regulates leaf initiation and maturation in rice. Kawakatsu T, et al. Plant Cell, 2006 Mar. PMID 16461585, Free PMC Article
  3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

General gene information

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Homology

NM_001084574.1
NM_129850.4
NM_201945.3

Gene Ontology Provided by TAIR

Process Evidence Code Pubs
involved_in positive regulation of growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of meiotic nuclear division IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
MEI2-like 2
NP_001078043.1
  • MEI2-like 2 (ML2); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), RNA recognition motif 2 (InterPro:IPR007201), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: MEI2-like protein 5 (TAIR:AT1G29400.2); Has 7605 Blast hits to 6029 proteins in 352 species: Archae - 6; Bacteria - 46; Metazoa - 4200; Fungi - 1128; Plants - 1425; Viruses - 0; Other Eukaryotes - 800 (source: NCBI BLink).
NP_565990.1
  • MEI2-like 2 (ML2); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), RNA recognition motif 2 (InterPro:IPR007201), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: MEI2-like protein 5 (TAIR:AT1G29400.2); Has 7613 Blast hits to 6033 proteins in 353 species: Archae - 6; Bacteria - 46; Metazoa - 4198; Fungi - 1128; Plants - 1433; Viruses - 0; Other Eukaryotes - 802 (source: NCBI BLink).
NP_973674.1
  • MEI2-like 2 (ML2); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), RNA recognition motif 2 (InterPro:IPR007201), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: MEI2-like protein 5 (TAIR:AT1G29400.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    17849819..17854553
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_129850.4 → NP_565990.1  MEI2-like 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_565990.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8S8G0, Q9ASS1, Q9SEU3, Q9SJG8
    UniProtKB/TrEMBL
    A0A178VQK0, A0A5S9X6K0
    Conserved Domains (4) summary
    pfam04059
    Location:679 → 775
    RRM_2; RNA recognition motif 2
    TIGR01628
    Location:149 → 471
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    cd12524
    Location:197 → 273
    RRM1_MEI2_like; RNA recognition motif 1 (RRM1) found in plant Mei2-like proteins
    cd12529
    Location:282 → 352
    RRM2_MEI2_like; RNA recognition motif 2 (RRM2) found in plant Mei2-like proteins

  2. NM_001084574.1 → NP_001078043.1  MEI2-like 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001078043.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A654F2L7, F4IP94
    Conserved Domains (4) summary
    pfam04059
    Location:666 → 762
    RRM_2; RNA recognition motif 2
    TIGR01628
    Location:136 → 458
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    cd12524
    Location:184 → 260
    RRM1_MEI2_like; RNA recognition motif 1 (RRM1) found in plant Mei2-like proteins
    cd12529
    Location:269 → 339
    RRM2_MEI2_like; RNA recognition motif 2 (RRM2) found in plant Mei2-like proteins

  3. NM_201945.3 → NP_973674.1  MEI2-like 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_973674.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A654F2L7, F4IP94
    Conserved Domains (4) summary
    pfam04059
    Location:666 → 762
    RRM_2; RNA recognition motif 2
    TIGR01628
    Location:136 → 458
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    cd12524
    Location:184 → 260
    RRM1_MEI2_like; RNA recognition motif 1 (RRM1) found in plant Mei2-like proteins
    cd12529
    Location:269 → 339
    RRM2_MEI2_like; RNA recognition motif 2 (RRM2) found in plant Mei2-like proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SJG8.2

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