U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LON4 lon protease 4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 819748, updated on 18-Sep-2024

Summary

Official Symbol
LON4
Official Full Name
lon protease 4
Primary source
TAIR:AT3G05790
Locus tag
AT3G05790
See related
Araport:AT3G05790
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F10A16.8; F10A16_8; lon protease 4
Summary
Encodes a member of the Lon protease-like proteins (Lon1/At5g26860, Lon2/At5g47040, Lon3/At3g05780, Lon4/At3g05790). Lon is a multifunctional ATP-dependent protease which exists in bacteria, archaea and within organelles in eukaryotic cells. Lon proteases are responsible for the degradation of abnormal, damaged and unstable proteins.
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See LON4 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
19
Sequence:
Chromosome: 3; NC_003074.8 (1719958..1725268, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene lon protease-like protein Neighboring gene lon protease 3 Neighboring gene AtBS1(activation-tagged BRI1 suppressor 1)-interacting factor 1 Neighboring gene ncRNA Neighboring gene ncRNA

General gene information

NM_111453.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in chloroplast IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrion ISM
Inferred from Sequence Model
more info
 

General protein information

Preferred Names
lon protease 4
NP_566259.1
  • lon protease 4 (LON4); FUNCTIONS IN: in 6 functions; INVOLVED IN: proteolysis; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA-type, core (InterPro:IPR003959), Peptidase S16, active site (InterPro:IPR008268), Peptidase S16, ATP-dependent protease La (InterPro:IPR004815), Peptidase S16, lon N-terminal (InterPro:IPR003111), Peptidase S16, Lon C-terminal (InterPro:IPR008269), ATPase, AAA+ type, core (InterPro:IPR003593), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), Peptidase S16, Lon protease, C-terminal (InterPro:IPR001984); BEST Arabidopsis thaliana protein match is: lon protease 1 (TAIR:AT5G26860.1); Has 17176 Blast hits to 15609 proteins in 2554 species: Archae - 375; Bacteria - 9875; Metazoa - 528; Fungi - 538; Plants - 282; Viruses - 3; Other Eukaryotes - 5575 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    1719958..1725268 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001337610.1NP_001325548.1  lon protease 4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LLK4, A0A5S9X9I7
  2. NM_111453.1NP_566259.1  lon protease 4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_566259.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9M9L7
    UniProtKB/TrEMBL
    A0A5S9X9I7
    Conserved Domains (5) summary
    smart00464
    Location:78125
    LON; Found in ATP-dependent protease La (LON)
    TIGR00763
    Location:81938
    lon; endopeptidase La
    pfam00004
    Location:452595
    AAA; ATPase family associated with various cellular activities (AAA)
    cl21455
    Location:408475
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    cl21678
    Location:734938
    ChlI; Subunit ChlI of Mg-chelatase