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NAC053 NAC domain containing protein 53 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 820214, updated on 18-Sep-2024

Summary

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Official Symbol
NAC053
Official Full Name
NAC domain containing protein 53
Primary source
TAIR:AT3G10500
Locus tag
AT3G10500
See related
Araport:AT3G10500
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AIF; anac053; ANAC053; ANTHER INDEHISCENCE FACTOR; NAC domain containing protein 53; NAC with transmembrane motif 1-like 4; NTL4
Summary
Encodes a transcriptional activator that is associated with the plasma membrane in a dormant form and is proteolytically cleaved to create a form that can enter the nucleus. It is thought to promote ROS production by binding directly to the promoters of genes encoding ROS biosynthetic enzymes during drought-induced leaf senescence.
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Genomic context

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See NAC053 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
5
Sequence:
Chromosome: 3; NC_003074.8 (3271217..3274176)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene NAC domain containing protein 50 Neighboring gene NAC domain containing protein 52 Neighboring gene Galactose oxidase/kelch repeat superfamily protein Neighboring gene hemoglobin 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The NAC-like gene ANTHER INDEHISCENCE FACTOR acts as a repressor that controls anther dehiscence by regulating genes in the jasmonate biosynthesis pathway in Arabidopsis. Shih CF, et al. J Exp Bot, 2014 Feb. PMID 24323506, Free PMC Article
  2. A NAC transcription factor NTL4 promotes reactive oxygen species production during drought-induced leaf senescence in Arabidopsis. Lee S, et al. Plant J, 2012 Jun. PMID 22313226
  3. A subcellular localization compendium of hydrogen peroxide-induced proteins. Inzé A, et al. Plant Cell Environ, 2012 Feb. PMID 21443605
  4. Establishment of Expression in the SHORTROOT-SCARECROW Transcriptional Cascade through Opposing Activities of Both Activators and Repressors. Sparks EE, et al. Dev Cell, 2016 Dec 5. PMID 27923776, Free PMC Article
  5. Promoter-based integration in plant defense regulation. Li B, et al. Plant Physiol, 2014 Dec. PMID 25352272, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The present data suggest a role for AIF in controlling anther dehiscence by suppressing the expression of jasmonic acid biosynthesis genes in Arabidopsis.[AIF]
    Title: The NAC-like gene ANTHER INDEHISCENCE FACTOR acts as a repressor that controls anther dehiscence by regulating genes in the jasmonate biosynthesis pathway in Arabidopsis.
  2. NTL4 acts as a molecular switch that couples ROS metabolism to drought-induced leaf senescence.
    Title: A NAC transcription factor NTL4 promotes reactive oxygen species production during drought-induced leaf senescence in Arabidopsis.
Submit: New GeneRIF Correction

General gene information

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NM_111885.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables transcription cis-regulatory region binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within drought recovery IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within leaf senescence IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within regulation of reactive oxygen species metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
  

General protein information

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Preferred Names
NAC domain containing protein 53
NP_566376.1
  • NAC domain containing protein 53 (NAC053); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity; INVOLVED IN: multicellular organismal development, regulation of transcription; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: No apical meristem (NAM) protein (InterPro:IPR003441); BEST Arabidopsis thaliana protein match is: NAC domain containing protein 2 (TAIR:AT5G04410.1); Has 3039 Blast hits to 3027 proteins in 85 species: Archae - 0; Bacteria - 10; Metazoa - 0; Fungi - 7; Plants - 3017; Viruses - 0; Other Eukaryotes - 5 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    3271217..3274176
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001337881.1 → NP_001326104.1  NAC domain containing protein 53 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LN95

  2. NM_111885.4 → NP_566376.1  NAC domain containing protein 53 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_566376.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LAH6, Q949N0, Q9SQY1
    UniProtKB/TrEMBL
    A0A178VIR2, A0A5S9XB33
    Conserved Domains (1) summary
    pfam02365
    Location:10 → 136
    NAM; No apical meristem (NAM) protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q949N0.1

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