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N2,N2-dimethylguanosine tRNA methyltransferase [ Arabidopsis thaliana (thale cress) ]

Gene ID: 820451, updated on 18-Sep-2024

Summary

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Official Full Name
N2,N2-dimethylguanosine tRNA methyltransferase
Primary source
TAIR:AT3G02320
Locus tag
AT3G02320
See related
Araport:AT3G02320
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F11A12.1; F11A12_1
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Genomic context

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Location:
chromosome: 3
Exon count:
12
Sequence:
Chromosome: 3; NC_003074.8 (469867..473717)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene K-box region and MADS-box transcription factor family protein Neighboring gene tRNA-Ile Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene tRNA-Asp

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of the enzymes responsible for m2,2G and acp3U formation on cytosolic tRNA from insects and plants. Funk HM, et al. PLoS One, 2020. PMID 33253256, Free PMC Article
  2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

General gene information

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NM_111099.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables tRNA (guanine(10)-N2)-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables tRNA (guanine(26)-N2)-dimethyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within tRNA modification IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
N2,N2-dimethylguanosine tRNA methyltransferase
NP_186881.2
  • N2,N2-dimethylguanosine tRNA methyltransferase; FUNCTIONS IN: RNA binding, tRNA (guanine-N2-)-methyltransferase activity; INVOLVED IN: tRNA processing; LOCATED IN: cellular_component unknown; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: N2,N2-dimethylguanosine tRNA methyltransferase (InterPro:IPR002905); BEST Arabidopsis thaliana protein match is: N2,N2-dimethylguanosine tRNA methyltransferase (TAIR:AT5G15810.1); Has 1019 Blast hits to 973 proteins in 363 species: Archae - 257; Bacteria - 68; Metazoa - 198; Fungi - 156; Plants - 105; Viruses - 0; Other Eukaryotes - 235 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    469867..473717
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_111099.5 → NP_186881.2  N2,N2-dimethylguanosine tRNA methyltransferase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_186881.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q682B9, Q9SRU7
    UniProtKB/TrEMBL
    A0A178VEZ9, A0A5S9X8Q3
    Conserved Domains (1) summary
    cl17173
    Location:10 → 466
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SRU7.3

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