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PA200 proteasome activating protein 200 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 820533, updated on 18-Sep-2024

Summary

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Official Symbol
PA200
Official Full Name
proteasome activating protein 200
Primary source
TAIR:AT3G13330
Locus tag
AT3G13330
See related
Araport:AT3G13330
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
proteasome activating protein 200
Summary
Encodes a protein that interacts with the 26S proteasome. Mutants are phenotypically indistinguishable from wild type plants under a variety of growth conditions. Protein levels increase upon exposure of seedlings to MG132, a specific, potent, reversible, and cell-permeable proteasome inhibitor.
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Genomic context

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See PA200 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
35
Sequence:
Chromosome: 3; NC_003074.8 (4319490..4330218, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Chaperone DnaJ-domain superfamily protein Neighboring gene cation exchanger 2 Neighboring gene tRNA-Asp Neighboring gene Transducin/WD40 repeat-like superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
  2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001338043.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables lysine-acetylated histone binding IEA
Inferred from Electronic Annotation
more info
  
enables peptidase activator activity IEA
Inferred from Electronic Annotation
more info
  
enables proteasome binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
proteasome activating protein 200
NP_001319538.1
  • proteasome activating protein 200 (PA200); FUNCTIONS IN: binding; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF3437 (InterPro:IPR021843), Armadillo-type fold (InterPro:IPR016024); Has 512 Blast hits to 355 proteins in 156 species: Archae - 0; Bacteria - 0; Metazoa - 127; Fungi - 262; Plants - 57; Viruses - 0; Other Eukaryotes - 66 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    4319490..4330218 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001338043.1 → NP_001319538.1  proteasome activating protein 200 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4JC97, Q8RXU1, Q9LTT5
    UniProtKB/TrEMBL
    A0A178VC52, A0A5S9XBQ3, A0A7G2EPN6
    Conserved Domains (3) summary
    sd00044
    Location:1582 → 1607
    HEAT; HEAT repeat [structural motif]
    pfam11919
    Location:1728 → 1810
    DUF3437; Domain of unknown function (DUF3437)
    pfam16507
    Location:309 → 807
    BLM10_mid; Proteasome-substrate-size regulator, mid region
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
F4JC97.2

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