ESM1 GDSL-like lipase/acylhydrolase superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: ESM1
Official Full Name: GDSL-like lipase/acylhydrolase superfamily protein
Primary source: TAIR:AT3G14210
Locus tag: AT3G14210
See related: Araport:AT3G14210
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: epithiospecifier modifier 1
Summary: A semidominant QTL which has an epistatic effect on the Epithiospecifier gene. Represses nitrile formation and favors isothiocyanate production during glucosinolate hydrolysis. The functional allele deters the insect herbivory T. ni.
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Genomic context

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See ESM1 in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 6

Sequence:: Chromosome: 3; NC_003074.8 (4729399..4731847)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The Epithiospecifier modifier 1 gene controlled to produce significant levels of indol-3-acetonitrile formation.
Title: ESP and ESM1 mediate indol-3-acetonitrile production from indol-3-ylmethyl glucosinolate in Arabidopsis.
EPITHIOSPECIFIER MODIFIER1 (ESM1) epistatically represses nitrile formation and favors isothiocyanate production in combination with ESP. The glucosinolate hydrolysis profile change influenced by ESM1 is associated with insect resistance[ESM1]
Title: The gene controlling the quantitative trait locus EPITHIOSPECIFIER MODIFIER1 alters glucosinolate hydrolysis and insect resistance in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001338114.1

Supported by ESTs:

NM_112278.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables hydrolase activity, acting on ester bonds	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within glucosinolate catabolic process	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within glucosinolate catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to insect	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in apoplast	HDA more info	PubMed
located_in chloroplast	HDA more info	PubMed
located_in chloroplast envelope	HDA more info	PubMed
located_in cytosol	HDA more info	PubMed
located_in cytosolic ribosome	HDA more info	PubMed
located_in extracellular region	ISM Inferred from Sequence Model more info
located_in nucleus	HDA more info	PubMed
located_in peroxisome	HDA more info	PubMed
located_in plant-type vacuole	HDA more info	PubMed
located_in plasmodesma	HDA more info	PubMed
located_in secretory vesicle	HDA more info	PubMed

General protein information

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Preferred Names: GDSL-like lipase/acylhydrolase superfamily protein

NP_188037.1

epithiospecifier modifier 1 (ESM1); FUNCTIONS IN: hydrolase activity, acting on ester bonds, carboxylesterase activity; INVOLVED IN: glucosinolate catabolic process, response to cold, defense response to bacterium, response to insect; LOCATED IN: in 8 components; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Lipase, GDSL (InterPro:IPR001087); BEST Arabidopsis thaliana protein match is: myrosinase-associated protein, putative (TAIR:AT1G54010.1); Has 1512 Blast hits to 1501 proteins in 69 species: Archae - 0; Bacteria - 44; Metazoa - 1; Fungi - 2; Plants - 1464; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

4729399..4731847

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_112278.3 → NP_188037.1 GDSL-like lipase/acylhydrolase superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_188037.1

Status: REVIEWED

UniProtKB/Swiss-Prot

A0MAV7, Q941A3, Q9LJG3

UniProtKB/TrEMBL

A0A178V7Z2

Conserved Domains (1) summary

cd01837
Location:36 → 344

SGNH_plant_lipase_like; SGNH_plant_lipase_like, a plant specific subfamily of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all ...
NM_001338114.1 → NP_001326872.1 GDSL-like lipase/acylhydrolase superfamily protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1I9LQL1