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ADT4 arogenate dehydratase 4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 823601, updated on 18-Sep-2024

Summary

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Official Symbol
ADT4
Official Full Name
arogenate dehydratase 4
Primary source
TAIR:AT3G44720
Locus tag
AT3G44720
See related
Araport:AT3G44720
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
arogenate dehydratase 4
Summary
Encodes a plastid-localized arogenate dehydratase involved in phenylalanine biosynthesis. Not less than six genes encoding ADT were identified in the Arabidopsis genome: ADT1 [At1g11790]; ADT2 [At3g07630]; ADT3 [At2g27820]; ADT4 [At3g44720]; ADT5 [At5g22630]; and ADT6 [At1g08250].
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Genomic context

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See ADT4 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
1
Sequence:
Chromosome: 3; NC_003074.8 (16271511..16273413)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene Plant thionin family protein Neighboring gene miscRNA Neighboring gene kinesin-like protein 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Reduced Arogenate Dehydratase Expression: Ramifications for Photosynthesis and Metabolism. Höhner R, et al. Plant Physiol, 2018 May. PMID 29523714, Free PMC Article
  2. Tyrosine and phenylalanine are synthesized within the plastids in Arabidopsis. Rippert P, et al. Plant Physiol, 2009 Mar. PMID 19136569, Free PMC Article
  3. Phenylalanine biosynthesis in Arabidopsis thaliana. Identification and characterization of arogenate dehydratases. Cho MH, et al. J Biol Chem, 2007 Oct 19. PMID 17726025
  4. Translational Regulation of Metabolic Dynamics during Effector-Triggered Immunity. Yoo H, et al. Mol Plant, 2020 Jan 6. PMID 31568832, Free PMC Article
  5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ADT4 role in photosynthesis and secondary metabolism.
    Title: Reduced Arogenate Dehydratase Expression: Ramifications for Photosynthesis and Metabolism.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_114340.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables arogenate dehydratase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables prephenate dehydratase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-phenylalanine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within defense response IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast IDA
Inferred from Direct Assay
more info
 PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
arogenate dehydratase 4
NP_190058.1
  • arogenate dehydratase 4 (ADT4); CONTAINS InterPro DOMAIN/s: Prephenate dehydratase (InterPro:IPR001086), Prephenate dehydratase, conserved site (InterPro:IPR018528); BEST Arabidopsis thaliana protein match is: arogenate dehydratase 5 (TAIR:AT5G22630.1); Has 7069 Blast hits to 7066 proteins in 2218 species: Archae - 179; Bacteria - 3950; Metazoa - 0; Fungi - 120; Plants - 261; Viruses - 0; Other Eukaryotes - 2559 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    16271511..16273413
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_114340.4 → NP_190058.1  arogenate dehydratase 4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_190058.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O22241
    UniProtKB/TrEMBL
    A0A5S9XHZ0
    Conserved Domains (3) summary
    cd04905
    Location:315 → 410
    ACT_CM-PDT; C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme
    PLN02317
    Location:29 → 416
    PLN02317; arogenate dehydratase
    cd13631
    Location:124 → 305
    PBP2_Ct-PDT_like; Catalytic domain of prephenate dehydratase from Chlorobium tepidum and similar proteins, subgroup 2; the type 2 periplasmic binding protein fold
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O22241.1

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