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HERK1 hercules receptor kinase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 823774, updated on 18-Sep-2024

Summary

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Official Symbol
HERK1
Official Full Name
hercules receptor kinase 1
Primary source
TAIR:AT3G46290
Locus tag
AT3G46290
See related
Araport:AT3G46290
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
hercules receptor kinase 1
Summary
Encodes HERCULES1 (HERK1), a receptor kinase regulated by Brassinosteroids and required for cell elongation during vegetative growth.
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Genomic context

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See HERK1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
2
Sequence:
Chromosome: 3; NC_003074.8 (17012500..17015885)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene receptor protein kinase-like protein Neighboring gene kinase-like protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional analysis of related CrRLK1L receptor-like kinases in pollen tube reception. Kessler SA, et al. EMBO Rep, 2015 Jan. PMID 25490905, Free PMC Article
  2. A family of receptor-like kinases are regulated by BES1 and involved in plant growth in Arabidopsis thaliana. Guo H, et al. Plant Signal Behav, 2009 Aug. PMID 19820315, Free PMC Article
  3. Three related receptor-like kinases are required for optimal cell elongation in Arabidopsis thaliana. Guo H, et al. Proc Natl Acad Sci U S A, 2009 May 5. PMID 19383785, Free PMC Article
  4. CrRLK1L receptor-like kinases HERK1 and ANJEA are female determinants of pollen tube reception. Galindo-Trigo S, et al. EMBO Rep, 2020 Feb 5. PMID 31867824, Free PMC Article
  5. RALF peptide signaling controls the polytubey block in Arabidopsis. Zhong S, et al. Science, 2022 Jan 21. PMID 35050671, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. CrRLK1L receptor-like kinases HERK1 and ANJEA are female determinants of pollen tube reception.
    Title: CrRLK1L receptor-like kinases HERK1 and ANJEA are female determinants of pollen tube reception.
  2. Extracellular domains of the FER, ANX1 and HERK1 receptor-like kinases are not interchangeable for their function in pollen tube reception, but their intracellular domains are.
    Title: Functional analysis of related CrRLK1L receptor-like kinases in pollen tube reception.
  3. 3 related receptor-like kinases, HERCULES1, THESEUS1, and FERONIA, transcriptionally induced by brassinosteroids are charcterized in this study. (HERCULES1)
    Title: Three related receptor-like kinases are required for optimal cell elongation in Arabidopsis thaliana.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_114497.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within brassinosteroid mediated signaling pathway IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in pollen tube guidance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in pollen tube reception IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within post-embryonic development IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within regulation of unidimensional cell growth IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within response to brassinosteroid IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within unidimensional cell growth IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
  
located_in filiform apparatus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane HDA PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasmodesma HDA PubMed 

General protein information

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Preferred Names
hercules receptor kinase 1
NP_190214.1
  • hercules receptor kinase 1 (HERK1); FUNCTIONS IN: protein kinase activity, kinase activity; INVOLVED IN: brassinosteroid mediated signaling pathway, post-embryonic development, response to brassinosteroid stimulus, unidimensional cell growth, regulation of unidimensional cell growth; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT5G59700.1); Has 116300 Blast hits to 115060 proteins in 4658 species: Archae - 101; Bacteria - 13233; Metazoa - 43205; Fungi - 9848; Plants - 32844; Viruses - 378; Other Eukaryotes - 16691 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    17012500..17015885
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_114497.4 → NP_190214.1  hercules receptor kinase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_190214.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9LX66, Q9SNA7
    UniProtKB/TrEMBL
    A0A5S9XJ34, A0A654FEL6
    Conserved Domains (2) summary
    cd14066
    Location:491 → 756
    STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
    pfam12819
    Location:33 → 380
    Malectin_like; Carbohydrate-binding protein of the ER
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LX66.1

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