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PPa4 pyrophosphorylase 4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 824530, updated on 18-Sep-2024

Summary

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Official Symbol
PPa4
Official Full Name
pyrophosphorylase 4
Primary source
TAIR:AT3G53620
Locus tag
AT3G53620
See related
Araport:AT3G53620
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtPPa4; pyrophosphorylase 4
Summary
Encodes a soluble protein with inorganic pyrophosphatase activity that is highly specific for Mg-inorganic pyrophosphate.
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Genomic context

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See PPa4 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
9
Sequence:
Chromosome: 3; NC_003074.8 (19880504..19883743)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene C2H2-type zinc finger family protein Neighboring gene RAB GTPase homolog 8 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Protein kinase superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Vacuolar H(+)-Pyrophosphatase and Cytosolic Soluble Pyrophosphatases Cooperatively Regulate Pyrophosphate Levels in Arabidopsis thaliana. Segami S, et al. Plant Cell, 2018 May. PMID 29691313, Free PMC Article
  2. Virus-induced gene silencing of plastidial soluble inorganic pyrophosphatase impairs essential leaf anabolic pathways and reduces drought stress tolerance in Nicotiana benthamiana. George GM, et al. Plant Physiol, 2010 Sep. PMID 20605913, Free PMC Article
  3. bHLH05 is an interaction partner of MYB51 and a novel regulator of glucosinolate biosynthesis in Arabidopsis. Frerigmann H, et al. Plant Physiol, 2014 Sep. PMID 25049362, Free PMC Article
  4. Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis. Klopffleisch K, et al. Mol Syst Biol, 2011 Sep 27. PMID 21952135, Free PMC Article
  5. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_115222.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables inorganic diphosphate phosphatase activity IDA
Inferred from Direct Assay
more info
  
enables inorganic diphosphate phosphatase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in phosphate-containing compound metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
pyrophosphorylase 4
NP_190930.1
  • pyrophosphorylase 4 (PPa4); FUNCTIONS IN: inorganic diphosphatase activity; INVOLVED IN: response to cadmium ion, metabolic process; LOCATED IN: membrane, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Inorganic pyrophosphatase (InterPro:IPR008162); BEST Arabidopsis thaliana protein match is: pyrophosphorylase 1 (TAIR:AT1G01050.1); Has 5938 Blast hits to 5938 proteins in 1824 species: Archae - 171; Bacteria - 4276; Metazoa - 240; Fungi - 260; Plants - 270; Viruses - 0; Other Eukaryotes - 721 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    19880504..19883743
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_115222.3 → NP_190930.1  pyrophosphorylase 4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_190930.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LA73, Q9LFF9
    UniProtKB/TrEMBL
    A0A178VKC0, A0A5S9XLB0
    Conserved Domains (1) summary
    PLN02373
    Location:29 → 216
    PLN02373; soluble inorganic pyrophosphatase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LFF9.1

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