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SINAT2 uncharacterized protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 824973, updated on 18-Sep-2024

Summary

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Official Symbol
SINAT2
Official Full Name
uncharacterized protein
Primary source
TAIR:AT3G58040
Locus tag
AT3G58040
See related
Araport:AT3G58040
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
seven in absentia of Arabidopsis 2
Summary
Encodes a RING finger domain containing protein that interacts with AtRAP2.2.
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Genomic context

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See SINAT2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
3
Sequence:
Chromosome: 3; NC_003074.8 (21488433..21491518)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene tRNA-Ser Neighboring gene uncharacterized protein Neighboring gene Cation efflux family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcription factor RAP2.2 and its interacting partner SINAT2: stable elements in the carotenogenesis of Arabidopsis leaves. Welsch R, et al. Plant Physiol, 2007 Nov. PMID 17873090, Free PMC Article
  2. 14-3-3 proteins contribute to autophagy by modulating SINAT-mediated degradation of ATG13. Qi H, et al. Plant Cell, 2022 Nov 29. PMID 36053201, Free PMC Article
  3. SINAT E3 ligases regulate the stability of the ESCRT component FREE1 in response to iron deficiency in plants. Xiao Z, et al. J Integr Plant Biol, 2020 Sep. PMID 32786047
  4. The tumor necrosis factor receptor-associated factor (TRAF)-like family protein SEVEN IN ABSENTIA 2 (SINA2) promotes drought tolerance in an ABA-dependent manner in Arabidopsis. Bao Y, et al. New Phytol, 2014 Apr. PMID 24350984
  5. TRAF Family Proteins Regulate Autophagy Dynamics by Modulating AUTOPHAGY PROTEIN6 Stability in Arabidopsis. Qi H, et al. Plant Cell, 2017 Apr. PMID 28351989, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The action of SINAT2 may explain the recalcitrance of AtRAP2.2 protein levels to change by altering AtRAP2.2 transcription.
    Title: Transcription factor RAP2.2 and its interacting partner SINAT2: stable elements in the carotenogenesis of Arabidopsis leaves.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_115666.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein ubiquitination IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein ubiquitination IPI
Inferred from Physical Interaction
more info
 PubMed 
involved_in regulation of autophagosome assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
uncharacterized protein
NP_001326739.1
  • seven in absentia of Arabidopsis 2
NP_001326740.1
  • seven in absentia of Arabidopsis 2
NP_191363.1
  • seven in absentia of Arabidopsis 2 (SINAT2); FUNCTIONS IN: protein binding; INVOLVED IN: multicellular organismal development, protein ubiquitination, ubiquitin-dependent protein catabolic process; LOCATED IN: nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: TRAF-like (InterPro:IPR008974), Seven-in-absentia protein, TRAF-like domain (InterPro:IPR018121), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, SIAH-type (InterPro:IPR013010), Seven In Absentia Homolog-type (InterPro:IPR013323), Seven-in-absentia protein, sina (InterPro:IPR004162), TRAF-type (InterPro:IPR013322); BEST Arabidopsis thaliana protein match is: Protein with RING/U-box and TRAF-like domains (TAIR:AT2G41980.1); Has 1862 Blast hits to 1847 proteins in 701 species: Archae - 0; Bacteria - 0; Metazoa - 1276; Fungi - 4; Plants - 482; Viruses - 0; Other Eukaryotes - 100 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    21488433..21491518
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001339902.1 → NP_001326740.1  uncharacterized protein AT3G58040 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9M2P4
    Conserved Domains (2) summary
    cd16571
    Location:58 → 96
    RING-HC_SIAHs; RING finger, HC subclass, found in Drosophila melanogaster protein Seven-in-Absentia (sina) and its homologs
    cl19105
    Location:102 → 215
    Sina; Seven in absentia (Sina) protein family, C-terminal substrate binding domain; composed of the Drosophila Sina protein, the mammalian Sina homolog (Siah), the plant protein SINAT5, and similar proteins. Sina, Siah and SINAT5 are RING-containing proteins ...

  2. NM_001339903.1 → NP_001326739.1  uncharacterized protein AT3G58040 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q0WNH5, Q1ECQ0, Q9M2P4
    UniProtKB/TrEMBL
    A0A178VHN9, A0A5S9XLU1
    Conserved Domains (2) summary
    cd16571
    Location:58 → 96
    RING-HC_SIAHs; RING finger, HC subclass, found in Drosophila melanogaster protein Seven-in-Absentia (sina) and its homologs
    pfam03145
    Location:102 → 301
    Sina; Seven in absentia protein family

  3. NM_115666.2 → NP_191363.1  uncharacterized protein AT3G58040 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_191363.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q0WNH5, Q1ECQ0, Q9M2P4
    UniProtKB/TrEMBL
    A0A178VHN9, A0A5S9XLU1
    Conserved Domains (2) summary
    cd16571
    Location:58 → 96
    RING-HC_SIAHs; RING finger, HC subclass, found in Drosophila melanogaster protein Seven-in-Absentia (sina) and its homologs
    pfam03145
    Location:102 → 301
    Sina; Seven in absentia protein family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9M2P4.1

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