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FUS6 COP9 signalosome complex subunit 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 825286, updated on 18-Sep-2024

Summary

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Official Symbol
FUS6
Official Full Name
COP9 signalosome complex subunit 1
Primary source
TAIR:AT3G61140
Locus tag
AT3G61140
See related
Araport:AT3G61140
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA FUSCA 6; AtCSN1; ATFUS6; ATSK31; CONSTITUTIVE PHOTOMORPHOGENIC 11; COP11; COP9 SIGNALOSOME SUBUNIT 1; CSN1; EMB78; EMBRYO DEFECTIVE 78; FUSCA 6; SHAGGY-LIKE KINASE 31; SK31
Summary
Represses photomorphogenesis and induces skotomorphogenesis in the dark. Component of the nuclear-localized COP9 complex. Mutants display striking purple coloration due to anthocyanin accumulation in their cotyledons, first become defective during embryogenesis and exhibit limited seedling development.
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Genomic context

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See FUS6 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
7
Sequence:
Chromosome: 3; NC_003074.8 (22626167..22630141)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene AGAMOUS-like 13 Neighboring gene galacturonosyltransferase 1 Neighboring gene homeodomain GLABROUS 1 Neighboring gene Protein kinase superfamily protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A FUSCA gene of Arabidopsis encodes a novel protein essential for plant development. Castle LA, et al. Plant Cell, 1994 Jan. PMID 8130643, Free PMC Article
  2. Characterization and purification of the mammalian COP9 complex, a conserved nuclear regulator initially identified as a repressor of photomorphogenesis in higher plants. Wei N, et al. Photochem Photobiol, 1998 Aug. PMID 9723217
  3. Evidence for FUS6 as a component of the nuclear-localized COP9 complex in Arabidopsis. Staub JM, et al. Plant Cell, 1996 Nov. PMID 8953769, Free PMC Article
  4. Arabidopsis FUSCA5 encodes a novel phosphoprotein that is a component of the COP9 complex. Karniol B, et al. Plant Cell, 1999 May. PMID 10330469, Free PMC Article
  5. The Arabidopsis homologue of an eIF3 complex subunit associates with the COP9 complex. Karniol B, et al. FEBS Lett, 1998 Nov 13. PMID 9849901

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. TSA1 interacts with CSN1 and is involved in Arabidopsis seedling development in darkness.
    Title: TSA1 interacts with CSN1/CSN and may be functionally involved in Arabidopsis seedling development in darkness.
  2. CSN1 can mediate COP1 nuclear translocation, and COP1 interacts with CSN1-NTD through its coiled-coil domain.
    Title: Regulation of COP1 nuclear localization by the COP9 signalosome via direct interaction with CSN1.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_115978.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within embryo development ending in seed dormancy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within hyperosmotic response IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within photomorphogenesis TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within protein deneddylation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within protein deneddylation TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within protein-containing complex assembly IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within response to absence of light IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to salt stress IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
part_of COP9 signalosome IDA
Inferred from Direct Assay
more info
 PubMed 
part_of COP9 signalosome TAS
Traceable Author Statement
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
COP9 signalosome complex subunit 1
NP_567109.1
  • FUSCA 6 (FUS6); CONTAINS InterPro DOMAIN/s: Proteasome component (PCI) domain (InterPro:IPR000717), 26S proteasome, regulatory subunit Rpn7 (InterPro:IPR019585); BEST Arabidopsis thaliana protein match is: COP9 signalosome complex-related / CSN complex-related (TAIR:AT3G12850.1); Has 1199 Blast hits to 1198 proteins in 240 species: Archae - 0; Bacteria - 0; Metazoa - 515; Fungi - 231; Plants - 316; Viruses - 0; Other Eukaryotes - 137 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    22626167..22630141
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_115978.4 → NP_567109.1  COP9 signalosome complex subunit 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_567109.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P45432, Q8GYL2, Q9C5F0, Q9M2E9, Q9M4G0
    UniProtKB/TrEMBL
    A0A178VFN7, A0A5S9XMN6
    Conserved Domains (2) summary
    pfam01399
    Location:293 → 397
    PCI; PCI domain
    pfam10602
    Location:104 → 278
    RPN7; 26S proteasome subunit RPN7
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P45432.2

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