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PANB2 Phosphoenolpyruvate carboxylase family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 825326, updated on 18-Sep-2024

Summary

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Official Symbol
PANB2
Official Full Name
Phosphoenolpyruvate carboxylase family protein
Primary source
TAIR:AT3G61530
Locus tag
AT3G61530
See related
Araport:AT3G61530
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
KETOPANTOATE HYDROXYMETHYLTRANSFERASE; KPHMT2
Summary
Encodes a ketopentoate hydroxymethyltransferase that appears to localize to the mitochondria. This protein is expected to play a role in pantothenate (vitamin B5) biosynthesis.
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Genomic context

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See PANB2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
6
Sequence:
Chromosome: 3; NC_003074.8 (22771405..22773790, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ACC synthase 1 Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene tRNA-Glu Neighboring gene RING/U-box superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Organisation of the pantothenate (vitamin B5) biosynthesis pathway in higher plants. Ottenhof HH, et al. Plant J, 2004 Jan. PMID 14675432
  2. Divalent metal ions in plant mitochondria and their role in interactions with proteins and oxidative stress-induced damage to respiratory function. Tan YF, et al. Plant Physiol, 2010 Feb. PMID 20018591, Free PMC Article
  3. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
  4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
  5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_116018.4
NM_202745.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables 3-methyl-2-oxobutanoate hydroxymethyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables 3-methyl-2-oxobutanoate hydroxymethyltransferase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables cobalt ion binding HDA PubMed 
enables zinc ion binding HDA PubMed 
Process Evidence Code Pubs
involved_in pantothenate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within pantothenate biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Phosphoenolpyruvate carboxylase family protein
NP_191712.1
  • PANB2; CONTAINS InterPro DOMAIN/s: Pyruvate/Phosphoenolpyruvate kinase, catalytic core (InterPro:IPR015813), Ketopantoate hydroxymethyltransferase (InterPro:IPR003700); BEST Arabidopsis thaliana protein match is: ketopantoate hydroxymethyltransferase 1 (TAIR:AT2G46110.1); Has 7570 Blast hits to 7570 proteins in 2036 species: Archae - 128; Bacteria - 4151; Metazoa - 4; Fungi - 140; Plants - 59; Viruses - 0; Other Eukaryotes - 3088 (source: NCBI BLink).
NP_974474.1
  • PANB2; CONTAINS InterPro DOMAIN/s: Pyruvate/Phosphoenolpyruvate kinase, catalytic core (InterPro:IPR015813), Ketopantoate hydroxymethyltransferase (InterPro:IPR003700); BEST Arabidopsis thaliana protein match is: ketopantoate hydroxymethyltransferase 1 (TAIR:AT2G46110.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    22771405..22773790 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_202745.4 → NP_974474.1  Phosphoenolpyruvate carboxylase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_974474.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9M315
    UniProtKB/TrEMBL
    A0A5S9XMS8, A0A654FJS9
    Conserved Domains (1) summary
    PLN02424
    Location:23 → 354
    PLN02424; ketopantoate hydroxymethyltransferase

  2. NM_116018.4 → NP_191712.1  Phosphoenolpyruvate carboxylase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_191712.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9M315
    UniProtKB/TrEMBL
    A0A5S9XMS8, A0A654FJS9
    Conserved Domains (1) summary
    PLN02424
    Location:23 → 354
    PLN02424; ketopantoate hydroxymethyltransferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9M315.1

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