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XT1 xylosyltransferase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 825446, updated on 18-Sep-2024

Summary

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Official Symbol
XT1
Official Full Name
xylosyltransferase 1
Primary source
TAIR:AT3G62720
Locus tag
AT3G62720
See related
Araport:AT3G62720
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATXT1; AtXXT1; XXT1; XYG XYLOSYLTRANSFERASE 1; xylosyltransferase 1
Summary
Encodes a protein with xylosyltransferase activity, which is specific for UDP-xylose as donor substrate and for oligosaccharides with a degree of polymerization >4. Although the enzyme utilizes either cellopentaose or cellohexaose, its activity is four-fold higher with cellohexaose as an acceptor compared to cellopentaose. The enzyme is able to add several xylosyl residues to the acceptor forming mono-, di- and trixylosylated polysaccharides.
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Genomic context

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See XT1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
2
Sequence:
Chromosome: 3; NC_003074.8 (23201032..23202988)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene multidrug resistance-associated protein 10 Neighboring gene Glycosyl hydrolase family protein Neighboring gene pseudo Neighboring gene desiccation-like protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Lack of xyloglucan in the cell walls of the Arabidopsis xxt1/xxt2 mutant results in specific increases in homogalacturonan and glucomannan. Sowinski EE, et al. Plant J, 2022 Apr. PMID 35041247
  2. Disrupting two Arabidopsis thaliana xylosyltransferase genes results in plants deficient in xyloglucan, a major primary cell wall component. Cavalier DM, et al. Plant Cell, 2008 Jun. PMID 18544630, Free PMC Article
  3. Two xyloglucan xylosyltransferases catalyze the addition of multiple xylosyl residues to cellohexaose. Cavalier DM, et al. J Biol Chem, 2006 Nov 10. PMID 16982611
  4. Mutations in multiple XXT genes of Arabidopsis reveal the complexity of xyloglucan biosynthesis. Zabotina OA, et al. Plant Physiol, 2012 Aug. PMID 22696020, Free PMC Article
  5. Arabidopsis GT34 family contains five xyloglucan α-1,6-xylosyltransferases. Vuttipongchaikij S, et al. New Phytol, 2012 Aug. PMID 22670626

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Lack of xyloglucan in the cell walls of the Arabidopsis xxt1/xxt2 mutant results in specific increases in homogalacturonan and glucomannan.
    Title: Lack of xyloglucan in the cell walls of the Arabidopsis xxt1/xxt2 mutant results in specific increases in homogalacturonan and glucomannan.
  2. The supramolecular organization of the CSLC4, XXT1, XXT2, and XXT5 proteins in Arabidopsis protoplasts, was investigated.
    Title: Xyloglucan xylosyltransferases XXT1, XXT2, and XXT5 and the glucan synthase CSLC4 form Golgi-localized multiprotein complexes.
  3. XXT1 and XXT2 are responsible for the bulk of the xylosylation of the glucan backbone, and at least one of these proteins must be present and active for xyloglucan to be made. XXT5 plays a significant but as yet uncharacterized role in this process.
    Title: Mutations in multiple XXT genes of Arabidopsis reveal the complexity of xyloglucan biosynthesis.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001035840.2
NM_116137.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables UDP-xylosyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables glycosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables xyloglucan 6-xylosyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within polysaccharide biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within root hair elongation IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within xyloglucan biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within xyloglucan metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus HDA PubMed 
located_in Golgi apparatus ISM
Inferred from Sequence Model
more info
  
located_in Golgi medial cisterna HDA PubMed 
located_in Golgi medial cisterna IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol HDA PubMed 
located_in endosome HDA PubMed 
located_in trans-Golgi network HDA PubMed 

General protein information

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Preferred Names
xylosyltransferase 1
NP_001030917.1
  • xylosyltransferase 1 (XT1); FUNCTIONS IN: xyloglucan 6-xylosyltransferase activity, UDP-xylosyltransferase activity, transferase activity, transferring glycosyl groups, transferase activity; INVOLVED IN: polysaccharide biosynthetic process, xyloglucan biosynthetic process, root hair elongation; LOCATED IN: mitochondrion, integral to membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Galactosyl transferase (InterPro:IPR008630); BEST Arabidopsis thaliana protein match is: UDP-xylosyltransferase 2 (TAIR:AT4G02500.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_191831.1
  • xylosyltransferase 1 (XT1); FUNCTIONS IN: xyloglucan 6-xylosyltransferase activity, UDP-xylosyltransferase activity, transferase activity, transferring glycosyl groups, transferase activity; INVOLVED IN: polysaccharide biosynthetic process, xyloglucan biosynthetic process, root hair elongation; LOCATED IN: mitochondrion, integral to membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Galactosyl transferase (InterPro:IPR008630); BEST Arabidopsis thaliana protein match is: UDP-xylosyltransferase 2 (TAIR:AT4G02500.1); Has 441 Blast hits to 440 proteins in 92 species: Archae - 0; Bacteria - 4; Metazoa - 0; Fungi - 134; Plants - 286; Viruses - 0; Other Eukaryotes - 17 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    23201032..23202988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001035840.2 → NP_001030917.1  xylosyltransferase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001030917.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B9DHH6, Q9LZJ3
    UniProtKB/TrEMBL
    A0A178VEJ0, A0A5S9XN48
    Conserved Domains (1) summary
    PLN03182
    Location:1 → 451
    PLN03182; xyloglucan 6-xylosyltransferase; Provisional

  2. NM_116137.3 → NP_191831.1  xylosyltransferase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_191831.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B9DHH6, Q9LZJ3
    UniProtKB/TrEMBL
    A0A178VEJ0, A0A5S9XN48
    Conserved Domains (1) summary
    PLN03182
    Location:1 → 451
    PLN03182; xyloglucan 6-xylosyltransferase; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LZJ3.1

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