APR1 APS reductase 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: APR1
Official Full Name: APS reductase 1
Primary source: TAIR:AT4G04610
Locus tag: AT4G04610
See related: Araport:AT4G04610
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE REDUCTASE; APR; APS REDUCTASE; APS reductase 1; ATAPR1; F4H6.13; F4H6_13; PAPS REDUCTASE HOMOLOG 19; PRH19
Summary: Encodes a protein disulfide isomerase-like (PDIL) protein, a member of a multigene family within the thioredoxin (TRX) superfamily. This protein also belongs to the adenosine 5'-phosphosulfate reductase-like (APRL) group.
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Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Adenosine 5' phosphosulfate reductase and sulfite oxidase regulate sulfite-induced water loss in Arabidopsis.
Title: Adenosine 5' phosphosulfate reductase and sulfite oxidase regulate sulfite-induced water loss in Arabidopsis.
structure-based functional studies of APR1C would extend knowledge of the molecular mechanism and regulation of APR
Title: Crystallization of the C-terminal redox domain of the sulfur-assimilatory enzyme APR1 from Arabidopsis thaliana.
HY5 plays an important role in regulation of APR1 and APR2 gene expression and plant sulfate assimilation
Title: The key enzyme of sulfate assimilation, adenosine 5'-phosphosulfate reductase, is regulated by HY5 in Arabidopsis.
extensive posttranscriptional regulation
Title: Complex signaling network in regulation of adenosine 5'-phosphosulfate reductase by salt stress in Arabidopsis roots.

Submit: New GeneRIF Correction

NM_116699.3

Function	Evidence Code	Pubs
enables adenylyl-sulfate reductase (glutathione) activity	IEA Inferred from Electronic Annotation more info
enables adenylyl-sulfate reductase activity	IDA Inferred from Direct Assay more info	PubMed
enables phosphoadenylyl-sulfate reductase (thioredoxin) activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within sulfate assimilation	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within sulfate assimilation	IGI Inferred from Genetic Interaction more info	PubMed
involved_in sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in chloroplast	ISS Inferred from Sequence or Structural Similarity more info	PubMed
located_in chloroplast stroma	IDA Inferred from Direct Assay more info	PubMed
NOT located_in chloroplast thylakoid	IDA Inferred from Direct Assay more info	PubMed
located_in plastid	TAS Traceable Author Statement more info	PubMed

NP_192370.1

APS reductase 1 (APR1); FUNCTIONS IN: adenylyl-sulfate reductase activity; INVOLVED IN: response to oxidative stress, sulfate reduction, sulfate assimilation; LOCATED IN: chloroplast, chloroplast stroma, plastid; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Thioredoxin-independent 5'-adenylylsulphate reductase (InterPro:IPR004508), Thioredoxin fold (InterPro:IPR012335), Phosphoadenosine phosphosulphate reductase (InterPro:IPR002500), Thioredoxin-like (InterPro:IPR017936), Thioredoxin domain (InterPro:IPR013766), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: APS reductase 3 (TAIR:AT4G21990.1); Has 5999 Blast hits to 5419 proteins in 1658 species: Archae - 169; Bacteria - 2693; Metazoa - 1288; Fungi - 563; Plants - 600; Viruses - 0; Other Eukaryotes - 686 (source: NCBI BLink).