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CLE44 CLAVATA3/ESR-RELATED 44 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 826934, updated on 18-Sep-2024

Summary

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Official Symbol
CLE44
Official Full Name
CLAVATA3/ESR-RELATED 44
Primary source
TAIR:AT4G13195
Locus tag
AT4G13195
See related
Araport:AT4G13195
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
CLAVATA3/ESR-RELATED 44
Summary
Belongs to a large gene family, called CLE for CLAVATA3/ESR-related, encoding small peptides with conserved carboxyl termini. The C-terminal 12 amino acid sequence of CLE44 is identical to that of a dodeca peptide (TDIF, tracheary element differentiation inhibitory factor) isolated from Arabidopsis and functions as a suppressor of plant stem cell differentiation. TDIF sequence is also identical to the C-terminal 12 amino acids of CLE41 (At3g24770). The protein is expressed in the vascular system and is involved in axillary bud formation.
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Genomic context

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See CLE44 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
1
Sequence:
Chromosome: 4; NC_003075.7 (7661792..7663261, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene zein-binding protein (Protein of unknown function, DUF593) Neighboring gene Ribosomal protein L13 family protein Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene Protein kinase superfamily protein Neighboring gene uncharacterized protein Neighboring gene Pectin lyase-like superfamily protein Neighboring gene miscRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dodeca-CLE peptides as suppressors of plant stem cell differentiation. Ito Y, et al. Science, 2006 Aug 11. PMID 16902140
  2. Non-cell-autonomous control of vascular stem cell fate by a CLE peptide/receptor system. Hirakawa Y, et al. Proc Natl Acad Sci U S A, 2008 Sep 30. PMID 18812507, Free PMC Article
  3. A novel function of TDIF-related peptides: promotion of axillary bud formation. Yaginuma H, et al. Plant Cell Physiol, 2011 Aug. PMID 21693505
  4. Perception of root-active CLE peptides requires CORYNE function in the phloem vasculature. Hazak O, et al. EMBO Rep, 2017 Aug. PMID 28607033, Free PMC Article
  5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_117389.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables receptor serine/threonine kinase binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within axillary shoot meristem initiation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in cell-cell signaling involved in cell fate commitment ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in maintenance of root meristem identity IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in phloem development IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within phloem or xylem histogenesis IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in procambium histogenesis IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of cell differentiation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in xylem development IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in apoplast IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
CLAVATA3/ESR-RELATED 44
NP_567397.1
  • CLAVATA3/ESR-RELATED 44 (CLE44); BEST Arabidopsis thaliana protein match is: CLAVATA3/ESR-RELATED 41 (TAIR:AT3G24770.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    7661792..7663261 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_117389.3 → NP_567397.1  CLAVATA3/ESR-RELATED 44 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_567397.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LFN1, Q941C5
    UniProtKB/TrEMBL
    A0A654FNQ0
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q941C5.1

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