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IP5PII myo-inositol polyphosphate 5-phosphatase 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 827526, updated on 18-Sep-2024

Summary

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Official Symbol
IP5PII
Official Full Name
myo-inositol polyphosphate 5-phosphatase 2
Primary source
TAIR:AT4G18010
Locus tag
AT4G18010
See related
Araport:AT4G18010
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
4; 5)P3 5-PHOSPHATASE II; 5PTASE2; AT5PTASE2; INOSITOL POLYPHOSPHATE 5-PHOSPHATASE II; INOSITOL(1; myo-inositol polyphosphate 5-phosphatase 2; T6K21.190; T6K21_190
Summary
Encodes an inositol polyphosphate 5-phosphatase that appears to have Type I activity. It can dephosphorylate IP3(inositol(1,4,5)P3) and IP4 (inositol(1,3,4,5)P4), but it does not appear to be active against phosphatidylinositol 4,5 bisphosphate. Overexpression of this gene renders plants insensitive to ABA in germination and growth assays.
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Genomic context

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See IP5PII in Genome Data Viewer
Location:
chromosome: 4
Exon count:
9
Sequence:
Chromosome: 4; NC_003075.7 (9990988..9994524, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene NAC domain containing protein 71 Neighboring gene uncharacterized protein Neighboring gene CheY-like two-component responsive regulator family protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Inositol polyphosphate 5-phosphatases 1 and 2 are required for regulating seedling growth. Gunesekera B, et al. Plant Physiol, 2007 Mar. PMID 17237190, Free PMC Article
  2. Arabidopsis PLC1 is required for secondary responses to abscisic acid signals. Sanchez JP, et al. Plant Cell, 2001 May. PMID 11340187, Free PMC Article
  3. Inositol polyphosphate phosphatidylinositol 5-phosphatase9 (At5ptase9) controls plant salt tolerance by regulating endocytosis. Golani Y, et al. Mol Plant, 2013 Nov. PMID 23658066
  4. Identification of ubiquitinated proteins in Arabidopsis. Manzano C, et al. Plant Mol Biol, 2008 Sep. PMID 18535787
  5. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001341251.1
NM_117911.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables inositol-1,4,5-trisphosphate 5-phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables inositol-polyphosphate 5-phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in inositol trisphosphate metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in phosphatidylinositol dephosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within response to abscisic acid IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within seed germination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in seedling development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
myo-inositol polyphosphate 5-phosphatase 2
NP_001319979.1
  • INOSITOL(1,4,5)P3 5-PHOSPHATASE II (IP5PII); CONTAINS InterPro DOMAIN/s: Inositol polyphosphate related phosphatase (InterPro:IPR000300), Endonuclease/exonuclease/phosphatase (InterPro:IPR005135); BEST Arabidopsis thaliana protein match is: DNAse I-like superfamily protein (TAIR:AT1G71710.2); Has 2627 Blast hits to 2054 proteins in 224 species: Archae - 0; Bacteria - 0; Metazoa - 957; Fungi - 640; Plants - 718; Viruses - 0; Other Eukaryotes - 312 (source: NCBI BLink).
NP_567547.1
  • myo-inositol polyphosphate 5-phosphatase 2 (5PTASE2); CONTAINS InterPro DOMAIN/s: Inositol polyphosphate related phosphatase (InterPro:IPR000300), Endonuclease/exonuclease/phosphatase (InterPro:IPR005135); BEST Arabidopsis thaliana protein match is: DNAse I-like superfamily protein (TAIR:AT1G71710.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    9990988..9994524 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001341251.1 → NP_001319979.1  myo-inositol polyphosphate 5-phosphatase 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UW61, A0A2H1ZEM5, A0A5S9XUC4

  2. NM_117911.4 → NP_567547.1  myo-inositol polyphosphate 5-phosphatase 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_567547.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O49700, Q9FUR2, Q9SNF1, Q9ZSC3
    UniProtKB/TrEMBL
    A0A178UW61, A0A5S9XUC4
    Conserved Domains (1) summary
    PLN03191
    Location:1 → 646
    PLN03191; Type I inositol-1,4,5-trisphosphate 5-phosphatase 2; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9FUR2.2

Gene LinkOut

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