KCO6 Ca2+ activated outward rectifying K+ channel 6 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: KCO6
Official Full Name: Ca2+ activated outward rectifying K+ channel 6
Primary source: TAIR:AT4G18160
Locus tag: AT4G18160
See related: Araport:AT4G18160
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATKCO6; ATTPK3; Ca2+ activated outward rectifying K+ channel 6; CA2+ ACTIVATED OUTWARD RECTIFYING K+ CHANNEL 6; F15J5.130; F15J5_130; TPK3
Summary: Encodes AtTPK3 (KCO6), a member of the Arabidopsis thaliana K+ channel family of AtTPK/KCO proteins.AtTPK3 is targeted to the vacuolar membrane. May form homomeric ion channels in vivo.
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Genomic context

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See KCO6 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 2

Sequence:: Chromosome: 4; NC_003075.7 (10055379..10058185)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Photosynthesis in Arabidopsis Is Unaffected by the Function of the Vacuolar K(+) Channel TPK3.
Title: Photosynthesis in Arabidopsis Is Unaffected by the Function of the Vacuolar K(+) Channel TPK3.
KCO6 does not form functional potassium channels when expressed in E. coli
Title: Arabidopsis thaliana vacuolar TPK channels form functional K⁺ uptake pathways in Escherichia coli.
the TPK3 channel manages the proton motive force necessary to convert photochemical energy into physiological functions.
Title: A thylakoid-located two-pore K+ channel controls photosynthetic light utilization in plants.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_117926.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables outward rectifier potassium channel activity	ISS Inferred from Sequence or Structural Similarity more info
enables potassium channel activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within cellular response to electrical stimulus	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within nonphotochemical quenching	IMP Inferred from Mutant Phenotype more info	PubMed
NOT acts_upstream_of_or_within photosynthesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within potassium ion export across plasma membrane	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within potassium ion import across plasma membrane	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within potassium ion transmembrane transport	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within thylakoid membrane organization	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
NOT located_in chloroplast	IDA Inferred from Direct Assay more info	PubMed
located_in chloroplast stromal thylakoid	IDA Inferred from Direct Assay more info	PubMed
located_in plant-type vacuole membrane	IDA Inferred from Direct Assay more info	PubMed
part_of potassium channel complex	IDA Inferred from Direct Assay more info	PubMed
located_in vacuole	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: Ca2+ activated outward rectifying K+ channel 6

NP_193550.1

Ca2+ activated outward rectifying K+ channel 6 (KCO6); FUNCTIONS IN: outward rectifier potassium channel activity; INVOLVED IN: potassium ion transport; LOCATED IN: plant-type vacuole membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Potassium channel, two pore-domain (InterPro:IPR003280), EF-Hand 1, calcium-binding site (InterPro:IPR018247), Ion transport 2 (InterPro:IPR013099); BEST Arabidopsis thaliana protein match is: Ca2+ activated outward rectifying K+ channel 2 (TAIR:AT5G46370.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

10055379..10058185

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_117926.3 → NP_193550.1 Ca2+ activated outward rectifying K+ channel 6 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_193550.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9SVV6

UniProtKB/TrEMBL

A0A178UWR8, A0A5S9XTU0, A0A7G2F3I8

Conserved Domains (2) summary

pfam07885
Location:156 → 237

Ion_trans_2; Ion channel

pfam13499
Location:374 → 431

EF-hand_7; EF-hand domain pair