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MYB98 myb domain protein 98 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 827611, updated on 18-Sep-2024

Summary

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Official Symbol
MYB98
Official Full Name
myb domain protein 98
Primary source
TAIR:AT4G18770
Locus tag
AT4G18770
See related
Araport:AT4G18770
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtMYB98; F28A21.180; F28A21_180; myb domain protein 98
Summary
MYB98 is a member of the R2R3-MYB gene family, the members of which likely encode transcription factors. Within an ovule, MYB98 is expressed exclusively in the synergid cells, and mutations in this gene affect the female gametophyte specifically. myb98 female gametophytes are affected in two unique features of the synergid cell, pollen tube guidance and the filiform apparatus, but are otherwise normal. This suggests that MYB98 controls the development of specific features within the synergid cell during female gametophyte development. MYB98 also is expressed in trichomes and endosperm. Homozygous myb98 mutants exhibit no sporophytic defects, including trichome and endosperm defects.
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Genomic context

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See MYB98 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
3
Sequence:
Chromosome: 4; NC_003075.7 (10311030..10313104)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene receptor like protein 51 Neighboring gene cellulose synthase family protein Neighboring gene ncRNA Neighboring gene NRAMP metal ion transporter family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cytoplasmic Ca2+ changes dynamically during the interaction of the pollen tube with synergid cells. Iwano M, et al. Development, 2012 Nov. PMID 23093426
  2. The MYB98 subcircuit of the synergid gene regulatory network includes genes directly and indirectly regulated by MYB98. Punwani JA, et al. Plant J, 2008 Aug. PMID 18410484
  3. Genome-wide expression profiling of the Arabidopsis female gametophyte identifies families of small, secreted proteins. Jones-Rhoades MW, et al. PLoS Genet, 2007 Oct. PMID 17937500, Free PMC Article
  4. MYB98 is required for pollen tube guidance and synergid cell differentiation in Arabidopsis. Kasahara RD, et al. Plant Cell, 2005 Nov. PMID 16214903, Free PMC Article
  5. MYB98 positively regulates a battery of synergid-expressed genes encoding filiform apparatus localized proteins. Punwani JA, et al. Plant Cell, 2007 Aug. PMID 17693534, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. 11 CRP3700 genes are shown to be regulated by a common cis-element, GTAACNT, and a multimer of this sequence confers MYB98-dependent synergid expression.
    Title: The MYB98 subcircuit of the synergid gene regulatory network includes genes directly and indirectly regulated by MYB98.
  2. These data suggest that MYB98 functions as a transcriptional regulator in the synergid cells and activates the expression of genes required for pollen tube guidance and filiform apparatus formation.
    Title: MYB98 positively regulates a battery of synergid-expressed genes encoding filiform apparatus localized proteins.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_117993.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA binding TAS
Traceable Author Statement
more info
 PubMed 
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables transcription cis-regulatory region binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables transcription cis-regulatory region binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within embryo sac development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within pollen tube guidance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in pollen tube guidance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of DNA-templated transcription TAS
Traceable Author Statement
more info
 PubMed 
involved_in regulation of embryo sac central cell differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of synergid differentiation IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within regulation of synergid differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of synergid differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
myb domain protein 98
NP_193612.1
  • myb domain protein 98 (MYB98); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: myb domain protein 118 (TAIR:AT3G27785.1); Has 10125 Blast hits to 8427 proteins in 562 species: Archae - 0; Bacteria - 3; Metazoa - 1026; Fungi - 830; Plants - 5955; Viruses - 3; Other Eukaryotes - 2308 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    10311030..10313104
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_117993.3 → NP_193612.1  myb domain protein 98 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_193612.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0MF81, Q3HSE6, Q9S7L2
    UniProtKB/TrEMBL
    A0A5S9XTR7, A0A654FQL8
    Conserved Domains (3) summary
    smart00717
    Location:217 → 265
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    pfam00249
    Location:269 → 311
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:220 → 280
    Myb_DNA-bind_6; Myb-like DNA-binding domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9S7L2.1

Gene LinkOut

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